Pyridoxal-5′-fosifate monohydrate CAS: 41468-25-1 99% Off-yera kugeza ifu yumuhondo yoroheje
| Umubare wa Cataloge | XD90390 |
| izina RY'IGICURUZWA | Pyridoxal-5'-fosifate monohydrate |
| URUBANZA | 41468-25-1 |
| Inzira ya molekulari | C8H10NO6P · H2O |
| Uburemere bwa molekile | 265.16 |
| Ibisobanuro birambuye | 2 kugeza 8 ° C. |
| Amategeko agenga ibiciro | 29362500 |
Kugaragaza ibicuruzwa
| Ibyuma biremereye | 20ppm max |
| Umubare wuzuye | 1000 cfu / g max |
| E.Coli | Ibibi |
| Salmonella | Ibibi |
| Gutakaza Kuma | 10.0% |
| Staphylococcus aureus | Ibibi |
| Suzuma | 99% |
| Kugaragara | Ifu yera-ifu yumuhondo yoroheje |
| Umusemburo & Kubara | 100 cfu / g max |
| Itariki yo gukora | TBC |
| Imyandikire | Ibibi |
| Pyridoxine (HPLC) | 0.01% max |
| PH (0,25% ag Igisubizo) | 2.6-3.0 |
Gusana neza kwa myelin muri CNS ikuze bisaba umusaruro ushimishije kandi mugihe cya proteine za myelin kugirango zitange ibyatsi bishya bya myelin.Uburyo bwibanze bwo kugenzura hamwe na molekulike igoye yo kuvugurura myelin, nyamara, iracyasobanuka neza.Hano, dukora iperereza ku ruhare rwa ERK MAP kinase yerekana muri iki gikorwa.Gusiba byanze bikunze Erk2 muri selile yumurongo wa oligodendrocyte byatumye reyelination itinda nyuma yo gukomeretsa demyelinating imbeba ikuze corpus callosum.Gutinda gusana byabaye nkibisubizo byihariye muguhindura proteine nini ya myelin, MBP.Mugihe ERK2 idahari, gukora poroteyine ya ribosomal S6 kinase (p70S6K) hamwe nintego yayo yo hepfo, protein ya ribosomal S6 (S6RP), yabangamiwe mugihe gikomeye mugihe preigeline oligodendrocytes yimukiraga mumasemburo akuze ashoboye kubyara sheel nshya.Rero, twasobanuye isano ikomeye hagati ya ERK MAP kinase yerekana cascade na mashini ya tra nslational byumwihariko muguhindura oligodendrocytes muri vivo.Ibisubizo byerekana uruhare rukomeye kuri ERK2 mugucunga ibisobanuro bya MBP, poroteyine ya myelin igaragara nkingirakamaro kugirango habeho ibisekuru bishya bya myelin nyuma yimvune zangiza muri CNS ikuze.
