Ibicuruzwa

Imiterere ya biofilm ku gukuramo amenyo irashobora gutera mucosite ya peri-implant na peri-implantitis.Izi ndwara zivurwa na antibiotike nka doxycycline (Doxy).Hano twakoresheje uburyo bwa electrochemicique ya cathodic polarisation kugirango twambike Doxy hejuru yinyuma yibikoresho byo kuvura amenyo.Ubuso bwa Doxy bwerekanwe kurekura guturika muri saline ya fosifate mugihe cya 24 h.Nyamara, umubare munini wa Doxy wagumye hejuru byibura ibyumweru 2 cyane cyane kuri 5 mA-3 h icyitegererezo hamwe na Doxy nyinshi, ibyo bikaba byerekana ko ari bacteriostatike yambere kandi ndende yubuso bwubatswe.Ubuhanga bwa chimie bwasesenguwe na x-ray ifoto ya elegitoroniki ya spekitroscopi na ion ya kabiri ya sprometrike.Ubuso bwa topografiya bwasuzumwe numurima woherezwa gusikana electron microscopi na profilometrie yubururu-urumuri.Igihe kinini cya polarisiyasi kuva 1h kugeza 5 h hamwe nubucucike buri hejuru kuva kuri cm 1 kugeza kuri 15 mA cm (-2) byaviriyemo Doxy nyinshi kuri surfa ce.Ubuso bwari butwikiriwe nigice cya Doxy kiri munsi ya 100 nm nta mpinduka nini zigaragara mubutaka.Umutungo wa antibacterial wubuso bwa Doxy wasesenguwe na biofilm hamwe niterambere rya planktonic ukoresheje epidermidis ya Staphylococcus.Ingero zometse kuri Doxy zagabanije kwegeranya biofilm no gukura kwa planktonique mu muco w’umuti, kandi binabuza gukura kwa bagiteri ku masahani.Ingaruka ya antibacterial yari ikomeye kuburugero rwa 5 mA-3 h yashizwemo na Doxy nyinshi ugereranije na 1 mA-1 h.Kubera iyo mpamvu, ubuso bwa abutment busize hamwe na Doxy bufite ubushobozi bwo gukumira ubukoroni bwa bagiteri iyo bwerekanwe mu kanwa.Doxy-coating irashobora kuba inzira ifatika yo kurwanya mucosite ya peri-implant no kwirinda ko itera muri peri-implantitis.