Ibicuruzwa

Citoline (CDP-choline) ni umuhuza wingenzi muri biosynthesis ya fosifatiqueylcholine, igice cyingenzi cyimyanya myakura.Byerekanwe gutanga ingaruka zingirakamaro haba muburyo bwinyamanswa ndetse no kugerageza kwa kanseri itari muri Amerika.Ubu bushakashatsi bwari bugizwe (dosiye 3 za citoline kugeza kuri 1 umwanya), kugenzurwa n’imodoka, kugerageza impumyi ebyiri mu bigo 21 byo muri Amerika.Umuti wagombaga gutangira mumasaha 24 nyuma yubwonko butangiye kandi byakomeje kumanwa ibyumweru 6.Isuzumabumenyi ryanyuma ryabaye ibyumweru 12.Abarwayi magana abiri na mirongo itanu n'icyenda bariyandikishije, hafi 65 muri buri tsinda.Igihe cyo kuva ubwonko bwatangiye kugeza kwivuza cyari amasaha 14.5, kandi nta tandukaniro rikomeye ryaranze imiterere yibanze hagati yaya matsinda usibye uburemere bwabarwayi.Itandukaniro rikomeye hagati yitsinda, rishyigikira imiti ya citoline, ryagaragaye mubisubizo byakozwe nkuko byapimwe na Barthel Index na Rankin, isuzuma rya neurologique nkuko ryapimwe n’ikigo cy’igihugu cy’ubuzima (NIH) cy’imitsi, n’imikorere y’ubwenge nkuko byapimwe na Ikizamini cya Mini Mini.Igihe igipimo fatizo cya NIH cyakoreshwaga nka covariate, itsinda rya citoline 500 mg na groupe citoline 2000 mg ryagize iterambere ryinshi ukurikije ijanisha ry’abarwayi bagize ingaruka nziza kuri Index ya Barthel mu minsi 90.Nta bintu bikomeye byatewe n'ibiyobyabwenge cyangwa impanuka zapfuye muri ubu bushakashatsi.Ubu bushakashatsi bwerekana ko citoline yo mu kanwa ishobora gukoreshwa neza hamwe n'ingaruka nkeya mu kuvura inkorora ikaze.Citicoline isa nkaho iteza imbere imikorere kandi ikagabanya icyuho cyubwonko hamwe na mg 500 za citoline bigaragara ko ari ikinini cyiza.