Ibicuruzwa

Nickel ni virusi igena virusi ya gastrici yumuntu Helicobacter pylori.Mubyukuri, H. pylori afite nikel-enzymes ebyiri zingirakamaro mugukoloniza vivo, [NiFe] hydrogenase na urease, ibintu byinshi bya virusi birimo ion 24 za nikel kuri buri kigo gikora.Kubera iyi misemburo yombi, kubaho kwa H. pylori gushingira kubintu byingenzi bya nikel, bivuze kugenzura neza ikwirakwizwa ryayo nububiko.Muri iri suzuma, tuzerekana inzira zo gukora enzymes za nikel hamwe nuburyo bwumwimerere buboneka muri H. pylori kugirango hafatwe, gucuruza no gukwirakwiza nikel hagati yimisemburo yombi.Harimo (i) sisitemu yo gufata nikel yo hanze, itwara FrpB4 TonB itwara abantu, (ii) guhuzagurika kwa poroteyine hamwe n’urusobe rw’imikoranire igira uruhare mu gucuruza nikel no gukwirakwiza hagati ya urease na hydrogenase na, (iii) Helicobacter yihariye ya nikel ihuza poroteyine. zifite uruhare mububiko bwa nikel kandi zishobora gukina uruhare rwa metallo-chaperone.Hanyuma, tuzaganira ku ruhare rw’abafatanyabikorwa ba nikel muri virusi kandi tubasabe nk'intego zo kuvura indwara zo kuvura indwara ya H. pylori.