Tetracycline hydrochloride CAS: 64-75-5 99% Ifu ya kristaline
| Umubare wa Cataloge | XD90366 |
| izina RY'IGICURUZWA | Tetracycline hydrochloride |
| URUBANZA | 64-75-5 |
| Inzira ya molekulari | C22H24N2O8 · HCl |
| Uburemere bwa molekile | 480.90 |
| Ibisobanuro birambuye | -15 kugeza kuri 20 ° C. |
| Amategeko agenga ibiciro | 29413000 |
Kugaragaza ibicuruzwa
| Umwanzuro | Yubahiriza BP2013, EP7, USP38 |
| Ibyuma biremereye | <0.005% |
| Umwanda umwe | <0.1% |
| Kumenyekanisha | IR, UV, HPLC, TLC |
| pH | 1.8-2.8 |
| Gutakaza Kuma | <2.0% |
| Ibisigisigi | n-Butanol <3000ppm |
| Suzuma | BP2013 / EP7 99% |
| Ashu | <0.5% |
| Guhinduranya neza | -240 kugeza -255 ° |
| Ubushobozi | USP 38:> 900ug / mg |
| Impanuka zose | <5% |
| Kugaragara | Ifu ya kristaline |
| 4-epianhydrotetracycline | <2% |
| Imipaka ya mikorobe | Bikubiyemo |
| 4-Epiteracycline | <3% |
| Anhydrotetracyoline | <0.5% |
| Chlortetracycline Hydrochloride | <0.5% |
| Igisubizo gisigaye | <100ppm |
Iterambere ryimiti igabanya ubukana ryahawe inshingano zo gukabya no gukoresha nabi imiti igabanya ubukana.Staphylococci ni kimwe mu bigize ibimera bisanzwe ariko nanone ni indwara zishobora gutera indwara zirwanya antibiyotike nyinshi zizwi.Kurwanya coagulase mbi staphylococci (CoNS) birasabwa guhinduka bitewe nigitutu cyiza cyo guhitamo nyuma yo kuvura antibiotique.Ubu bushakashatsi bwakoze iperereza ku kuba icyenda gikoreshwa cyane mu mikorobe y’inkari z’abantu ziva mu bitaro by’ibitaro bibiri byo muri Gana bijyanye no kurwanya CoNS.Inkari na CoNS byapimwe (n = 246 na n = 96) bivuye ku barwayi bo mu bitaro bibiri byo muri Gana.CoNS yamenyekanye ikoresheje Gram irangi, ikizamini cya coagulase, na MALDI-TOF / MS, kandi kwanduza mikorobe kwanduza mikorobe 12 zikoreshwa cyane byagenwe no gukwirakwiza disiki.Byongeye kandi uburyo bwo gusesengura bwateguwe kugirango hamenyekane imiti icyenda ikoreshwa cyane muri mikorobe muri Gana hakoreshejwe gukuramo ph-ase ifatanije na HPLC-MS / MS ukoresheje ionisiyoneri ya spray.Inshuro nyinshi zo kurwanya CoNS zagaragaye kuri penisiline V (98%), trimethoprim (67%), na tetracycline (63%).S. haemolyticus niyo yakunze kwigunga (75%), ikurikirwa na S. epidermidis (13%) na S. hominis (6%).S. haemolyticus nayo yari ubwoko bwerekana ubwinshi bwo kurwanya (82%).69% bya CoNS yitaruye barwanya ibiyobyabwenge byinshi (≧ 4 antibiotique) naho 45% bya CoNS birwanya methicilline.Imiti igabanya ubukana yagaragaye muri 64% y’urugero rw’inkari zasesenguwe (n = 121) aho imiti yica mikorobe ikunze kugaragara ni ciprofloxacin (30%), trimethoprim (27%), na metronidazole (17%).Ibyagaragaye cyane muri ubu bushakashatsi ni uko ubwinshi bw’imiti yica mikorobe yagaragaye mu nkari bwakunze kugaragara kuruta ikoreshwa ry’abarwayi kandi ubwinshi bw’indwara ya S. haemolyticus irwanya cyane ubundi bwoko bwa CoNS bwihanganira igihe habonetse imiti igabanya ubukana mu nkari.
