Tazobactam Cas: 89786-04-9
| Umubare wa Cataloge | XD92373 |
| izina RY'IGICURUZWA | Tazobactam |
| URUBANZA | 89786-04-9 |
| Imiterere ya molekularila | C10H12N4O5S |
| Uburemere bwa molekile | 300.29 |
| Ibisobanuro birambuye | -15 kugeza kuri 20 ° C. |
| Amategeko agenga ibiciro | 29419000 |
Kugaragaza ibicuruzwa
| Kugaragara | Ifu yera kugeza yera |
| Assay | 99% min |
| Amazi | <0.5% |
| Kuzenguruka byihariye | +127 kugeza kuri +139 |
| Ibyuma biremereye | <20ppm |
| Ibisigisigi kuri Ignition | <0.1% |
| Impanuka zose | <1.0% |
Tazobactam ni acide penisillanic aside sulfone isa nubuyobozi busa na sulbactam.Nibintu bikomeye β-lactamaseinhibitor kurusha sulbactam kandi ifite ibikorwa byagutse cyane kuruta acide clavulanic.Ifite antibacterialactivite idakomeye.Tazobactam iraboneka muri dose-dose, inshinge zatewe hamwe na piperacillin, insimburangingo yagutse ya penisillinconsisting ya 8: 1 ya sodium ya piperacillin na tazobactamsodium kuburemere kandi igurishwa mwizina ryubucuruzi Zosyn.Imiti ya farumasi yimiti yombi irasa cyane.Byombi bigira igice gito cyubuzima (t1 / 2 hour isaha 1), ni proteinbound ntoya, ifite metabolisme nkeya cyane, kandi isohoka muburyo budakora muminkari yibanda cyane.
Ibimenyetso byemejwe kuri piperacillin - tazobactamcombination harimo kuvura appendicite, postpartumendometritis, nindwara ya pelvic inflammatory yatewe na β-lactamase - itanga E. coli na Bacteroides spp., Indwara zuruhu nuruhu rwatewe na β-lactamase - itangaS.aureus, n'umusonga byatewe na β-lactamase - itanga imbaraga za grippe H.
