Streptavidin kuva Streptomyces avidinii CAS: 9013-20-1
Umubare wa Cataloge | XD90329 |
izina RY'IGICURUZWA | Streptavidin kuva Streptomyces avidinii |
URUBANZA | 9013-20-1 |
Inzira ya molekulari | C14H17BrClNO2S |
Uburemere bwa molekile | 378.71 |
Ibisobanuro birambuye | -15 kugeza kuri 20 ° C. |
Amategeko agenga ibiciro | 35040090 |
Kugaragaza ibicuruzwa
Kugaragara | Ifu yera |
Suzuma | 99% |
Kubushakashatsi ukoreshe gusa, ntabwo ari ugukoresha abantu | gukoresha ubushakashatsi gusa, ntabwo ari ugukoresha abantu |
Alkyne-hinged 3-fluorosialyl fluoride (DFSA) irimo itsinda rya alkyne yerekanwe ko ari uburyo bushingiye ku ntego yihariye idasubirwaho ya sialidase.Ikigereranyo kirinzwe na ester DFSA (PDFSA) nicyerekezo kibanza cya DFSA cyagenewe gukoreshwa mungingo nzima, kandi cyerekanwe gukora kode ya covalent hamwe na virusi, bagiteri, na sialidase yabantu.Iyonge ya fluorosialyl-enzyme irashobora guhuzwa na biotine ya azide yometse kuri kanda reaction hanyuma ikamenyekana na signal ya streptavidin yihariye.Amazi ya chromatografiya-rusange ya sprometrike / isesengura rusange rya spicerometrike ku bice bya peptide peptide yerekana ko umuvuduko wa 3-fluorosialyl uhindura ibisigazwa bya tirozine ya sialidase.DFSA yakoreshejwe mu kwerekana ubwandu bw'ibicurane no gusuzuma virusi ishobora kwanduza aside oseltamivir yo kurwanya ibicurane, mu gihe PDFSA yakoreshejwe mu kwerekana amashusho y’imihindagurikire y’ibikorwa bya sialidase mu ngirabuzimafatizo.