Iodoacetamide Cas: 144-48-9 98% Umweru kugeza umuhondo ukomeye
Umubare wa Cataloge | XD90247 |
izina RY'IGICURUZWA | Iodoacetamide |
URUBANZA | 144-48-9 |
Inzira ya molekulari | C2H4INO |
Uburemere bwa molekile | 184.96 |
Ibisobanuro birambuye | Ibidukikije |
Amategeko agenga ibiciro | 29241900 |
Kugaragaza ibicuruzwa
Gutakaza Kuma | <1% |
Suzuma | ≥98% |
Azote | 7.2 - 7.8% |
Kugaragara | Umweru kugeza umuhondo ukomeye |
Gukemura muri methanol | Hafi ya mucyo |
Isesengura ryibanze rya Carbone | 12.5 - 13.2% |
α-Iodoacetamide ni uruganda rukoreshwa nka electrophile muguhindura covalent ibisigazwa bya nucleophilique kuri proteyine (cysteine, methionine, histidine).Iyo uhinduye ibisigisigi bikora-bisigara bya poroteyine ya sisitemu, α-Iodoacetamide ikora nka inhibitor idasubirwaho yiyi misemburo.
Gukoresha: Irashobora gukoreshwa nka protease inhibitor CH2ICONH2.Kimwe na acide iyode, irashobora guhagarika bidasubirwaho imisemburo ya SH binyuze mubitekerezo bikurikira.R-SH + ICH2CONH2 → RS-CH2CONH2 + HI
Imikoreshereze: Alkylation reagents ya histidine na sisitemu muri proteomics, kubikurikirana bya peptide na inhibitor ya enzyme.Ikoreshwa kandi muri synthesis.