D-Valine Cas: 640-68-6 C5H11NO2
| Umubare wa Cataloge | XD90291 |
| izina RY'IGICURUZWA | D-Valine |
| URUBANZA | 640-68-6 |
| Inzira ya molekulari | C5H11NO2 |
| Uburemere bwa molekile | 117.14634 |
| Ibisobanuro birambuye | Icyumba cy'icyumba |
| Amategeko agenga ibiciro | 29224995 |
Kugaragaza ibicuruzwa
| Suzuma | 99% |
| Kugaragara | Ifu yera |
| Ubucucike | 1.2000 (igereranya) |
| Ingingo yo gushonga | > 295 ° C (subl.) (Lit.) |
| Ingingo yo guteka | 213,6 ° C kuri 760 mmHg |
| Ingingo ya Flash | 83 ℃ |
| Ironderero | -27 ° (C = 8, 6mol / L HCl) |
| Gukemura | 56 g / L (20 ° C) |
| Amazi meza | 56 g / L (20 ºC) |
| PSA | 63.32000 |
| LogP | 0.75460 |
| Kuzenguruka byihariye | -27.5 º (c = 5, 5N HCl) |
| Igikorwa cyiza | [α] 23 / D −32.0 kugeza −24.0 °, c = 8 muri 6 M HCl |
Abagore barwaye syndrome ya antifosifolipide (APS) bafite ibyago byinshi byo gutakaza inda inshuro nyinshi (RPL) na preeclampsia.Antibodiyite za antifosifolipide (aPL) zihindura imikorere ya trophoblast.Umuti ufite uburemere buke bwa heparin (LMWH) bigabanya ibyago bya RPL ariko ntabwo preeclampsia.Byongeye kandi, LMWH itera trophoblast sFlt-1 kurekura, ibintu birwanya angiogenic bifitanye isano na preeclampsia.Kubera ko kubura vitamine D bifitanye isano na APS na preeclampsia, ubu bushakashatsi bwashatse kumenya ingaruka za vitamine D ku mikorere ya trophoblast mu gushyiraho APL na LMWH.Umuyoboro wa mbere w’abantu batatu mu gihembwe cya mbere cya trophoblast (HTR8) n’umuco wambere wa trophoblast wavuwe cyangwa cyangwa udafite aPL imbere no kubura vitamine D, LMWH cyangwa byombi.Gusohora kwa Trophoblast ya cytokine ikongora hamwe na angiogenic byapimwe na ELISA.Vitamine D yonyine cyangwa ifatanije na LMWH yongereye imbaraga za APP iterwa na trophoblast inflammatory selile muri HTR8 n'imico y'ibanze.Mugihe vitamine D itagize icyo ihindura kuri moderi ya APL ihindagurika yibintu bya angiogenic muri trophoblast yambere, yabujije cyane irekurwa rya LMWH iterwa na sFlt-1.LMWH ifatanije na vitamine D irashobora kuba ingirakamaro kuruta kuvura imiti imwe ikumira APL -yatewe na trophoblast inflammation no guhindura LMWH iterwa na sFlt-1.
