Cytidine Cas: 65-46-3 Ifu ya kirisiti yera 99%
| Umubare wa Cataloge | XD90586 |
| izina RY'IGICURUZWA | Cytidine |
| URUBANZA | 65-46-3 |
| Inzira ya molekulari | C9H13N3O5 |
| Uburemere bwa molekile | 243.22 |
| Ibisobanuro birambuye | Ibidukikije |
| Amategeko agenga ibiciro | 29349990 |
Kugaragaza ibicuruzwa
| Kugaragara | Ifu ya kirisiti yera |
| Suzuma | 99% |
| Ibyuma biremereye | <20ppm |
| Imiti yimiti | C9H13N3O5 |
| Gutakaza Kuma | <0.5% |
| Ibisigisigi kuri Ignition | <0,10% |
Gutanga ingirabuzimafatizo ya deoxynucleoside triphosphates (DNTPs) ni ingenzi cyane mu kwigana no gusana ADN.Muri ubu bushakashatsi, twasesenguye uruhare rwa CMP / UMP kinase (CMPK), enzyme itera CDP, mugusana ADN.Gukomanga kwa CMPK bidindiza gusana ADN mugihe cyo gukira kwangirika kwa UV mu ngirabuzimafatizo zabuze serumu ariko ntabwo biri muri selile zitabuze serumu.Gutanga ibintu bidasanzwe bya cytidine cyangwa deoxycytidine byorohereza gusana ADN biterwa na CMPK mu ngirabuzimafatizo zabuze serumu, byerekana ko synthesis ya dCDP cyangwa CDP igena igipimo cyo gusana.Ariko, gukomanga kwa CMPK ntabwo bigira ingaruka kumurongo uhoraho wa dCTP muma selile yabuze.Twahise dusanga aho CMPK iherereye kuri ADN yangiritse no kuyikora hamwe na Tip60 hamwe na reductase ya ribonucleotide.Isesengura ryacu ryerekanye ko N-terminal 32-amino-acide ya CMPK isabwa kugirango yinjizwe mu bibanza byangiza ADN mu buryo bushingiye kuri Tip60.Ongera ugaragaze ubwoko bwishyamba ariko ntabwo N-terminus yasibwe CMPK igarura imikorere yo gusana ADN muri selile ya CMPK.Twasabye ko gushiraho urubuga rwihariye rwa DCDP binyuze muri CMPK rutanga uburyo bwo koroshya ADN mu ngirabuzimafatizo zabuze serumu.
