Ibicuruzwa

Gel ya Chitosan-dextran yakoreshejwe nka antihemostatike na antadhesive agent nyuma yo kubagwa sinus ya endoscopique.Kubera ko biofilm ya Staphylococcus aureus yagize uruhare muri rhinosinusite idakira, ubu bushakashatsi bwari bugamije kurushaho gukora iperereza kuri (i) kurwanya ibibyimba, (ii) kubuza biofilm ya bagiteri, (iii) ingaruka ziterwa na antivroliferative, na (iv) imiti ikiza ibikomere bya chitosani na gelo ya chitosan-dextran. . aureus enterotoxine B (SEB) hamwe nuburozi bwa syndrome de toxic (TSST), na (iv) kuri biofilm ya S. aureus.Chitosan yagize uruhare runini mu kugabanya imvugo ya IL-8 nyuma ya TSST na SEB.Chitosan yagize uruhare runini mu kugabanya imvugo ya IL-8 ya fibroblast idahagarikwa yerekana ingaruka zayo zo kurwanya inflammatory kuri fibroblast muri ad isease leta.Gel ya Chitosan-dextran yerekanye antibiyofilm ikomeye kuri 50% (v / v) yibanze muri vitro.Dextran, yonyine, yerekanye antibiyofilm yibintu 1.25% (w / v).Chitosan, yonyine, yagabanije ikwirakwizwa rya fibroblast igera kuri 82% yo gukwirakwizwa no kugenzura chitosan-dextran gel yagabanije ikwirakwizwa rya fibroblast igera kuri 0,04% yo gukwirakwiza.Ugereranije no kutagenzura imiti, gel ya chitosan-dextran yatinze cyane igipimo cyo gukira ibikomere mu masaha 48 yambere yubushakashatsi. Gel ya Chitosan-dextran yagabanije ikwirakwizwa rya fibroblast nigihe cyo gukiza ibikomere, byerekana uburyo bushoboka bwo kugabanya ibifatika muri posturgurgie igihe.Chitosan yagabanije urwego rwa IL-8, yerekana imiti irwanya inflammatory.Chitosan-dextran gel hamwe nubuvuzi bwa dextran byerekanaga antibiyofilm muburyo bwacu.