Ibicuruzwa

4-Methylumbelliferyl β-D-glucopyranoside yakoreshejwe nka substrate: · muri glucosylceramidase β enzyme yibikorwa mu bice bikungahaye kuri lysosome biva mu bice bya hippocampal neuron · muri β-glucosidase mu gihe cyo gusembura umusemburo · kugeza glucocerebrosidase 1 (GBA1) bifitanye isano na glucosidase 1 (GBA1). ibikorwa muri macrophage selile (RAW)

4-Methylumbelliferyl β-D-glucopyranoside ni insimburangingo ya enzymatique ya glycosidase.Byakoreshejwe nka substrate ya β- glucosidase kuva enterococci.

Turamenyesha ko abaterankunga ba glycoside yoroshye bashobora guhindura cyane uburinganire bwa glycosyltransferase-catalizike reaction, bigahindura isukari ya NDP-isukari ikava muri endothermic ikajya mubikorwa bidasanzwe.Kugirango tugaragaze akamaro k'imihindagurikire yubushyuhe bwa termodinamike, turagaragaza synthesis ya glycosyltransferase-catalizike ya 22 ya nucleotide yisukari itangwa nabaterankunga boroheje ba sukari ya aromatic, kimwe nuburyo bujyanye no gushiraho isukari nucleotide nkimbaraga zitera murwego rwa glycosyltransferase-catalizike reaction ntoya-molekile glycodiversification.Aba baterankunga boroheje ba aromatic banashoboje gukora ibara rusange rya glycosyltransfer, ikoreshwa mubuvumbuzi bwibiyobyabwenge, protein protein nubundi bushakashatsi bwibanze bushingiye kuri nucleotide.Ubu bushakashatsi bwibanze ku gitekerezo rusange kivuga ko NDP-isukari ari 'ingufu nyinshi' zitanga isukari iyo zivanywe mu miterere gakondo y’ibinyabuzima.