Ibicuruzwa

2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone (TMS-D-glucose lactone) ni imiti y’imiti izwiho gukoreshwa muri synthesis organique, cyane cyane mubijyanye na chimie ya karubone.Nibikomoka kuri D-glucose, isukari isanzwe ibaho, kandi ifite imitungo idasanzwe ituma igira akamaro muburyo butandukanye bwimiti.Bimwe mubikoreshwa byambere bya TMS-D-glucose lactone ni nkitsinda ririnda chimie ya karubone.Carbohydrates, harimo isukari, irashobora kugira amatsinda menshi ya hydroxyl, ishobora kwitwara hamwe nizindi reagent cyangwa guhinduka muburyo budakenewe mugihe cya synthesis.Muguhitamo kurinda amatsinda yihariye ya hydroxyl ukoresheje lactone ya TMS-D-glucose, abahanga mu bya shimi barashobora kugenzura ibyagezweho kandi bagakoresha uburyo bwiza bwa karubone.Nyuma yuko ibyifuzo byifuzwa birangiye, amatsinda arinda arashobora gukurwaho byoroshye, agaragaza ibicuruzwa byifuzwa.TMS-D-glucose lactone nayo isanga porogaramu nkigihe gito muguhuza ibikomoka kuri karubone nziza.Muguhitamo guhindura hydroxyl matsinda ya TMS-D-glucose lactone, abahanga mu bya shimi barashobora kwinjiza amatsinda menshi yimikorere cyangwa ibindi bisimburanya muri molekile ya karubone.Ibi bituma hashyirwaho ibinyabuzima bitandukanye bishingiye kuri karubone-hydrata hamwe nibishobora gukoreshwa muri farumasi, kwisiga, hamwe nibikoresho bya siyanse. Byongeye kandi, TMS-D-glucose lactone ikoreshwa muguhuza abaterankunga ba glycosil kugirango reaction ya glycosylation.Glycosylation ni intambwe yingenzi mu gushiraho imigozi ya glycoside, ikaba ari ngombwa mu kubaka karubone ndetse na glycoconjugates.TMS-D-glucose lactone irashobora guhinduka mubaterankunga ba glycosyl, ikora nkumuhuza woguhindura reaction ya glycosylation, bigafasha guhuza karubone yandi ma molekile.Ikindi kandi, TMS-D-glucose lactone ikoreshwa mugukora polymers zishingiye kuri karubone.Mugukoresha TMS-D-glucose lactone kubitekerezo bya polymerisiyonike, abahanga mu bya shimi barashobora gukora iminyururu ya polymer cyangwa imiyoboro hamwe na karubone ya hydroxyde.Iyi polymers ya karubone irashobora kugira ibintu byihariye kandi irashobora kubona ibisabwa mubice nka sisitemu yo gutanga ibiyobyabwenge, bioengineering, na biomaterial. Birakwiye ko tumenya ko lactone ya TMS-D-glucose igomba gukoreshwa neza bitewe nubushuhe bwayo hamwe nubushyuhe bwikirere.Ubusanzwe ibikwa kandi igakoreshwa munsi yikirere cya azote cyangwa argon kugirango birinde kwangirika.Mu ncamake, 2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone (TMS-D-glucose lactone) ni uruganda rwinshi rukoreshwa cyane muri chimie ya karubone.Mubikorwa byibanze harimo kurinda chimie yitsinda, synthesis intermediaire, gushiraho abaterankunga ba glycosyl, no gukora polymers zishingiye kuri karubone.Mugukoresha TMS-D-glucose lactone muribwo buryo, abahanga mu bya shimi barashobora kugera ku kugenzura neza imyuka ya karubone ndetse no gukora ibikomoka kuri karubone nziza hamwe nibishobora gukoreshwa mubice bitandukanye.