Ibicuruzwa

Ifumbire ya 2 - ({(5S) -2-oxo-3- [4- 3.Ibikomoka kuri Isoindole byavuzwe ko bifite imiti itandukanye ya farumasi, harimo antitumor, anti-inflammatory, na antimicrobial. Umuvuduko wa oxazolidinone, uhagarariwe na 1,3-oxazolidin-5-yl, uzwiho ibikorwa bya antibacterial.Oxazolidinone yakoreshejwe nk'ibintu by'ingenzi muri antibiyotike, cyane cyane kurwanya bagiteri zidakira imiti.Ibi birerekana ko urugimbu rushobora kugira ubushobozi nka antibacterial agent. Kubaho kwa morfolineone ya morfoline, ihagarariwe nitsinda rya 4- (3-oxomorpholin-4-yl) ya fenyl, byongera ubundi buryo bugoye kubikoresha.Morpholine yinjijwe cyane mubintu bivura imiti kubera ubushobozi bwayo bwo guhura nibinyabuzima bitandukanye.Itsinda rya oxo kuri morpholinone rishobora kuzamura imikoranire yikigo nintego zihariye, bikagira uruhare runini mu kubaka ibiyobyabwenge no kwiteza imbere. 2-oxo-3- [4- (3-oxomorpholin-4-yl) fenyl] - - Itsinda rya 1,3-oxazolidin-5-yl, rifatanije na isoindole yibanze, rigize urubuga nyamukuru rwibintu.Iri tsinda ryihariye ryimiti yerekana ko rishobora kugirana imikoranire nintego z’ibinyabuzima nka enzymes cyangwa reseptors. Muri rusange, ukurikije imiterere y’urwo ruganda, rufite ubushobozi bwo kwerekana ibikorwa bya farumasi muri antibacterial, anti-inflammatory, ndetse n’ahandi hantu hashobora kuvurwa.Nyamara, imikoreshereze yihariye nuburyo bwibikorwa byakenera kugenwa hifashishijwe ubundi bushakashatsi, harimo muri vitro ndetse no mubushakashatsi bwa vivo, kugirango hamenyekane imikorere yabyo hamwe numwirondoro wumutekano.Mu gusoza, ibice 2 - ({(5S) -2-oxo -3- [4-. n'imiti kubera imiterere yayo igoye hamwe nibishobora kuba bya farumasi.Ubushakashatsi bw'ejo hazaza burakenewe kugirango tumenye imikoreshereze yihariye, uburyo bwo kuvura bushobora gukoreshwa, hamwe nibikorwa rusange.