Ibicuruzwa

Hydrochloride ya Vancomycin ni antibiyotike ya glycopeptide kandi ni umunyu wa hydrochloride wa vancomycine.Ni ifu yera cyangwa yera isa nifu ya kristaline mubushyuhe bwicyumba.Uburyo bwibikorwa byabwo ni uko bushobora guhuza cyane na poly-terminus alanyl-alanine ya precursor peptide iherereye ku rukuta rw'utugingo ngengabuzima ya bagiteri yoroheje, ikabuza biosynthesis ya peptide glycan polymer igizwe n'urukuta rwa bagiteri, bityo bikaviramo inenge y'urukuta rw'akagari no gukomeza kwica bagiteri.Byongeye kandi, birashoboka kandi guhindura uburyo bwimikorere ya bagiteri ya selile, hanyuma ugahitamo guhagarika synthesis ya RNA.Ikiranga hydrochloride ya vancomycine ningaruka zikomeye za bagiteri ziterwa na bagiteri nziza ya Gram nka Staphylococcus aureus, epidermidis ya Staphylococcus, pyogène Streptococcus, na pneumoniae streptococcus.Ifite kandi ingaruka zimwe na zimwe zo kurwanya bagiteri kuri Streptococci anaerobius, Clostridium difficile, Bacillus anthracis, Actinomycetes, Corynebacterium diphtheria, Neisseria gonorrhoeae, Streptococcus viridans, Streptococcus bovis, na Streptococcus faecalis.Nyamara, kuri bacteri nyinshi za Gram-mbi, Mycobacterium, ubwoko bwa Rickettsia, Chlamydia cyangwa fungi, ntabwo byemewe.Irakoreshwa mubuvuzi bwanduye bwatewe na methicilline irwanya Staphylococcus aureus nizindi bagiteri: sepsis, endocarditis, osteomyelitis, arthritis, gutwika ibikomere, ihahamuka ryo kubaga nizindi ndwara zanduye, umusonga, ibihaha, empyema, peritonite, meningite, pseudomembranous colitis, hamwe nuruhu nindwara zoroshye.Nihitamo ryibanze kubarwayi bafite allergique kuri penisiline kandi barwaye endococcal endocarditis na Corynebacterium (class diphtheria sp) endocarditis.