Ibicuruzwa

Thiamphenicol ni antibiyotike ya chloramphenicol yagutse, ikora cyane kuri bagiteri-mbi ya bagiteri kuruta bagiteri nziza.Ku bushyuhe bwicyumba, ni ifu yera cyangwa yera ya pisitori ya kirisiti cyangwa kristu, ishobora kwinjizwa vuba kandi rwose no gutangwa kumanwa, kimwe no gusohoka cyane cyane muri prototype iva muminkari kugirango metabolism.Irakoreshwa mubuvuzi bwo kuvura imyanya y'ubuhumekero, inzira yinkari, umwijima na gallbladder, tifoyide nubundi kubaga amara, indwara z’abagore n’indwara za ENT.Cyane cyane mundwara zoroheje ni byiza cyane.Ifite imiterere isa na chloramphenicol.Methyl sulfone yayo yasimbuye nitro ya chloramphenicol, yagabanije uburozi bwayo, kandi muri vivo ibikorwa byayo birwanya antibacterial bikubye inshuro 2,5-5 kurenza chloramphenicol.Kuri bagiteri-nziza ya bagiteri, nka streptococcus pneumoniae na hemolytic streptococcus, igira ingaruka zikomeye za antibacterial, mugihe kuri bagiteri-mbi ya garama, nka Neisseria gonorrhoeae, meningococcus, ibihaha Bacteroides, E. coli, Vibrio kolera, Shigella na grippe bacillus, ifite kandi ingaruka zikomeye za antibacterial.Kuri bagiteri ya anaerobic, Rickettsia na amibe, igira ingaruka za antibacterial murwego runaka.Ifite uburyo bumwe bwo kurwanya mikorobe hamwe na chloramphenicol, ibuza cyane guhuza intungamubiri za poroteyine.Uyu muti winjizwa vuba nubuyobozi bwo munwa, bugera kumaraso menshi mumasaha abiri.Igice cyacyo cya kabiri ni amasaha 5, ni kirekire kuruta chloramphenicol.Indwara ya bagiteri irwanya umusaraba wuzuye hamwe na chloramphenicol, mugihe bagiteri zifite ibintu bimwe na bimwe byo guhangana na tetracycline.

Thiamphenicol nayo ifite ingaruka zikomeye zo gukingira indwara, ikaba ari immunosuppressant nziza.Uburyo bwibikorwa byabwo butandukanye cyane nizindi miti ikingira indwara.Ingaruka zo gukingira indwara ziruta inshuro nyinshi kurenza chloramphenicol.Irashobora kuba nk'iyaguka ryiza ryo guhinduranya no kubaga allogeneic transplantation.