Terbinafine hydrochloride Cas: 78628-80-5
Umubare wa Cataloge | XD92374 |
izina RY'IGICURUZWA | Terbinafine hydrochloride |
URUBANZA | 78628-80-5 |
Imiterere ya molekularila | C21H25N · HCl |
Uburemere bwa molekile | 327.89 |
Ibisobanuro birambuye | -15 kugeza kuri 20 ° C. |
Amategeko agenga ibiciro | 29214900 |
Kugaragaza ibicuruzwa
Kugaragara | Ifu yera |
Assay | 99% min |
Ingingo yo gushonga | 204-208 ° C. |
ububiko bwa temp. | 15-25 ° C. |
gukemura | methanol: gushonga50mg / mL |
erbinafine hydrochloride ni ubwoko bwimiti yagutse ya dermatologue allyl amine imiti igabanya ubukana.Yatunganijwe n’Ubusuwisi Novartis mu myaka ya za 1980, igaragara ku isoko ry’Ubwongereza ku nshuro ya mbere mu 1991. Yemejwe na FDA yo muri Amerika ku biyobyabwenge bya OTC mu 1996, igaragara no ku isoko ry’Amerika muri ubwo buryo umwaka.Kugeza ubu, ibiyobyabwenge bigurishwa mu bihugu birenga 90 by'ijambo.Irashobora guhangayikisha ibibazo bitinze kwangirika kwa biologiya ya fungus sterol, guhitamo guhitamo ibikorwa bya fungal squalene ring oxydease, kandi ikabuza epoxidation ya squalene mugukora ingirabuzimafatizo ya selile, bityo ikica cyangwa ikabuza gukora ibihumyo.Birakwiye kuvura uruhu rwa candidiasis, nka tinea manuum, tinea, tinea, inzoka zo mu mubiri, tinea versicolor, niwo muti mwiza wo kuvura onikomycose.
Terbinafine hydrochloride yinjiye mu cyiciro cya mbere cy’igihugu cyatangaje ububiko bwa OTC mu 2000. Iki gicuruzwa ni icy'imiti igabanya ubukana.Ifite ingaruka zikomeye ku kwanduza ibihumyo, kandi irashobora gukiza indwara nyinshi zuruhu rwibihumyo ukoresheje hanze.