Ibicuruzwa

Indwara ya diyabete ifitanye isano no kurwego rwo hasi rwo gutwika no guhagarika umutima.Bupleurum Polysaccharide (BPs), yitandukanije na Bupleurum smithii var.parvifolium ifite anti-inflammatory na anti-okiside.Nyamara, bike bizwi ku ngaruka zabyo zo kuvura diyabete.Muri ubu bushakashatsi, ubushakashatsi bwakozwe ku ngaruka za BP ku kugabanya diyabete ndetse n’uburyo bwashingiweho.Imiterere yimbeba ya diyabete yashizweho hakoreshejwe inshinge zikurikirana zatewe na streptozotocine (100 mg / kg uburemere bwumubiri) muminsi ibiri.Imbeba zifite glucose yamaraso irenga 16.8mmol / L zatoranijwe kugirango zigerageze.Imbeba za diyabete zatanzwe mu kanwa na BP (30 na 60 mg / kg) rimwe kumunsi iminsi 35.BP ntabwo yagabanije cyane urugero rwa glucose yamaraso, ahubwo yongereye na serumu insuline na glycogene yumwijima mu mbeba za diyabete ugereranije nimbeba ntangarugero.Byongeye kandi, imiyoborere ya BPs yatezimbere imvugo ya insuline kandi ihagarika apoptose muri pancreas yimbeba za diyabete.Ubushakashatsi bwakozwe na Histopathologie bwerekanye kandi ko BP yarinze pancreas n'umwijima kwangirika kwa okiside na inflammatory.Ibisubizo byerekana ko BP irinda pancreatic β selile na hepatocytes yumwijima na diabete ya ameliorate, ifitanye isano na anti-oxyde na anti-inflammatory.