N- (2-Acetamide) acide iminodiacetic Cas: 26239-55-4 99% Ifu yera
Umubare wa Cataloge | XD90194 |
izina RY'IGICURUZWA | ADA (N - (- 2-Acetamido) acide iminodiacetic) |
URUBANZA | 26239-55-4 |
Inzira ya molekulari | C6H10N2O5 |
Uburemere bwa molekile | 190.15 |
Ibisobanuro birambuye | Ibidukikije |
Amategeko agenga ibiciro | 29241900 |
Kugaragaza ibicuruzwa
Fe | <5ppm |
Pb | <5ppm |
Gutakaza Kuma | <0.5% |
Ivu ryuzuye | <0.1% |
Kugaragara | Ifu yera |
Abandi | Nta na kimwe |
Igihe cyo gusenyuka (9g muri 91ml 1M NaOH, Gukurura Magnetique) | <1min |
A300 (9% muri 1 M NaOH) | <0.08% |
Umubare wibisobanuro Byarebwaga muri titre curve | Babiri gusa |
pH Urwego rusobanura Titration Iherezo rya kabiri | 9.1 - 10.1 |
Gukemura (9% muri 1M NaOH) | Birasobanutse kandi bitagira ibara |
Itariki yo gukora | |
Amazi KF | <1% |
Suzuma (Titration) ku buryo bwumye | > 99.0% |
Infrared | Bikubiyemo |
Nucleoside adenosine ikora kuri sisitemu y'imitsi n'umutima n'imitsi ikoresheje reseptor ya A2A (A2AR).Mu rwego rwo gusubiza urugero rwa ogisijeni mu ngingo, kwibanda kwa plasma ya adenosine bigengwa cyane cyane binyuze muri synthesis yayo na CD73 no kubitesha agaciro na adenosine deaminase (ADA).CD-selile-selile endopeptidase CD26 igenzura ubukana bwa peptide ya vasoactive na antioxydeant bityo ikagenga itangwa rya ogisijeni mumubiri hamwe nigisubizo cya okiside.Nubwo gukabya gukabije kwa adenosine, CD73, ADA, A2AR, na CD26 mugusubiza hypoxia byanditse neza, ingaruka ziterwa na hyperoxic na hyperbaric kuri ibi bintu zikwiye kwitabwaho.Imbeba n'umurongo wa seline Chem-3 yerekana A2AR byagaragaye kuri 0.21 bar O2, 0,79 bar N2 (imiterere yisi; normoxia);1 bar O2 (hyperoxia);2 bar O2 (hyperbaric hyperoxia);0.21 bar O2, 1,79 bar N2 (hyperbaria).Kwibanda kwa plasma ya Adenosine, CD73, ADA, imvugo ya A2AR, nibikorwa bya CD26 byavuzwe muri vivo, naho umusaruro wa cAMP wabwiwe muri selile.Kubireba vivo, 1) hyperoxia yagabanije urwego rwa plasma ya adenosine na T selile ya CD26 ibikorwa, mugihe byongereye CD73 imvugo nurwego rwa ADA;2) hyperbaric hyperoxia yakunze kongera inzira;na 3) hyperbariya yonyine ntiyagize uruhare runini kuri ibi bipimo.Mu bwonko no muri selile, 1) hyperoxia yagabanije imvugo ya A2AR;2) hyperbaric hyperoxia yongereye inzira;na 3) hyperbariya yonyine yerekanye ingaruka zikomeye.Twabonye uburyo busa bujyanye na synthesis ya A2AR mRNA mubwonko no gukora cAMP muri selile Chem-3.Rero urwego rwo hejuru rwa ogisijeni rwakunze kugabanya inzira ya adenosinergique nibikorwa bya CD26.Hyperbaria yonyine yagize ingaruka kumvugo ya A2AR gusa no gukora cAMP.Turaganira ku buryo ubwo buryo buterwa na hyperoxygene bushobora kugabanya, binyuze muri vasoconstriction, umwuka wa ogisijeni uhabwa ingirabuzimafatizo no gukora amoko ya ogisijeni ikora.