Glutathione yagabanije Cas: 70-18-8 98-101% Birasobanutse kandi bitagira ibara
| Umubare wa Cataloge | XD90284 |
| izina RY'IGICURUZWA | Glutathione yagabanutse |
| URUBANZA | 70-18-8 |
| Inzira ya molekulari | C10H17N3O6S |
| Uburemere bwa molekile | 307.32 |
| Ibisobanuro birambuye | 2 kugeza 8 ° C. |
| Amategeko agenga ibiciro | 29309098 |
Kugaragaza ibicuruzwa
| Suzuma | 98% - 101% |
| Kugaragara | Ifu ya kirisiti yera |
| Icyiciro | EP 7.0 |
| Umwanda A. | <0.5% |
| Umwanda B. | <0.5% |
| Ibyuma biremereye | <10ppm |
| Indwara ya bagiteri | <0.10EU / mg |
| Umwanda C. | <1.5% |
| Umwanda D. | <1.0% |
| Gutakaza Kuma | <0.5% |
| Gukemura | Kubora mumazi kubusa, gushonga gake muri Ethanol na methylene chloride |
| Icyuma | <10ppm |
| Chloride | <200ppm |
| Kugaragara k'umuti | Birasobanutse kandi bitagira ibara |
| Guhinduranya neza | -15.5 kugeza -17.5 |
| Impanuka zose | <2,5% |
| Amonium | <200ppm |
| Ivu ryuzuye | <0.1% |
| Sulfate | <300ppm |
| Umwanda E. | <0.5% |
Guhindura poroteyine nyuma yubusobanuro, nka fosifori ya tirozine, bigenga imikoranire ya poroteyine-proteyine (PPIs) zikomeye mu gutunganya ibimenyetso na fenotipike ya selile.Twaguye umusemburo washyizweho sisitemu ebyiri-ivanga ikoresha protein kinase yumuntu kugirango isesengure rya fosifore-tyrosine (pY) -Bishingiye kuri PPIs muburyo butaziguye, muburyo bunini.Twabonye 292 cyane cyane pY-ishingiye kuri PPIs yerekanaga umwihariko cyane kubijyanye na kinase hamwe na poroteyine zikorana kandi twemeza igice kinini mubushakashatsi bwakozwe na immunoprecipitation buturuka ku ngirangingo z’inyamabere.Hafi ya kimwe cya gatandatu cyimikoranire ihuzwa numurongo uzwi ukurikirana uhuza motifs mugihe ubwinshi bwa pY-PPIs bwahujwe nindi epitopa yumurongo cyangwa igengwa nubundi buryo bwo kumenyekana.Isesengura ry’urusobe ryagaragaje ko ibyabaye byamenyekanye byerekanwa na poroteyine ihuza cyane na poroteyine igenewe ibimenyetso byerekana inzira ya kanseri.Dukoresheje ibipimo bifatika, protein yuzuza ntation hamwe na fenotipiki yo gusoma kugirango iranga imikoranire ya pY iterwa na TSPAN2 (tetraspanin 2) na GRB2 cyangwa PIK3R3 (p55γ), turatanga urugero rwerekana ko PPI zombi zishingiye kuri pY zitegeka fenotipike ya kanseri.
