Erythromycin CAS: 114-07-8 99% Ifu ya kirisiti yera
Umubare wa Cataloge | XD90353 |
izina RY'IGICURUZWA | Erythromycin |
URUBANZA | 114-07-8 |
Inzira ya molekulari | C37H67NO13 |
Uburemere bwa molekile | 733.93 |
Ibisobanuro birambuye | Ibidukikije |
Amategeko agenga ibiciro | 29415000 |
Kugaragaza ibicuruzwa
Kumenyekanisha | Kugereranya IR kugereranya na USP RS |
Amazi | 10% max |
Ethanol | 0.5% max |
Ibisigisigi kuri Ignition | 0.2% max |
Suzuma | 99% |
Kuzenguruka byihariye | -71 ° kugeza kuri -78 ° |
Kugaragara | Ifu ya kirisiti yera |
Crystallinity | Yujuje ibisabwa |
Erythromycin B. | 12.0% |
ErythromycinC | 5.0% |
Imipaka ya thiocyanate | 0.3% |
Propanol | 0.5% max |
N-butyl acetate | 0.5% max |
Erythromycin A enol ether | 0.3% |
Ibintu byose bifitanye isano | 3.0% max |
Muri ubu bushakashatsi, twasuzumye imikoreshereze y’imiti igabanya ubukana hamwe na bine ya lipide yerekana urugero rwigana uturemangingo tw’inyamabere hamwe na Gram-positif na -negative bacterial membrane hanyuma tunasesengura kinetics ihuza dukoresheje tekinike ya plasmon resonance (SPR).Ibintu byatoranijwe kandi byihariye biranga imiti igabanya ubukana bwa lipid membrane byagereranijwe, kandi ibipimo bya kinetic byasesenguwe hakoreshejwe uburyo bwa leta ebyiri zerekana.Isesengura ryororoka ryo guhuza kinetics ryaragaragaye.Vancomyicn, teicoplanin, erythromycine, na linezolid yerekanaga imikoranire mike na bine ya lipide muri sisitemu ya SPR.Kurundi ruhande, ibigereranyo bya vancomycin byerekanaga imikoranire nicyitegererezo cya lipid membrane muri sisitemu ya SPR.Ibintu byatoranijwe kandi byihariye biranga vancomycine igereranya na lipide membrane byaganiriweho hashingiwe ku makuru yo mu bikorwa bya antibacterial vitro ndetse namakuru yacu ahuza isano ya D-alanyl-D-ala icyenda cyurukuta rwa pentapeptide yakiriwe na SPR.Uburyo bwibikorwa bya antibacterial kurwanya Staphylococcus aureus na enterococci irwanya vancomycine bishobora gusuzumwa hifashishijwe isano ihuza hamwe nubuhanga bwacu bwa SPR.Ibisubizo byerekana ko uburyo bwa SPR bushobora gukoreshwa cyane kugirango hamenyekane ibintu biranga guhuza, nko guhitamo no kwiharira, bya mikorobe myinshi yica mikorobe.