![Bis [2-Hydroxyethyl] imino Tris- (Hydroxymethyl) -methane Cas: 6976-37-0 99% Ishusho Yerekanwe](http://cdn.globalso.com/xdbiochems/6976-37-0.jpg)
Bis [2-Hydroxyethyl] imino Tris- (Hydroxymethyl) -methane Cas: 6976-37-0 99%
| Umubare wa Cataloge | XD90111 |
| izina RY'IGICURUZWA | BIS-TRIS (Bis (2-hydroxyethyl) amino-tris (hydroxymethyl) metani) |
| URUBANZA | 6976-37-0 |
| Inzira ya molekulari | C8H20NO5 |
| Uburemere bwa molekile | 210.2476 |
| Ibisobanuro birambuye | Ibidukikije |
| Amategeko agenga ibiciro | 2922190090 |
Kugaragaza ibicuruzwa
| Ibyuma biremereye | <10ppm |
| Ibisigisigi kuri Ignition | <0.1% |
| Pka | 6.3-6.7 |
| Kugaragara | Ifu yera ya Crystalline |
| Gukemura (1M muri H20) | Birasobanutse kandi Byuzuye |
| pH (1M muri H2O) | 9.0-11.0 |
| Ubushuhe (LOD) | 1.0% max. |
| Suzuma (Titration ku cyuma) | 99.0% min. |
Buffer, ikoreshwa mugutahura creine-creatinase;ikoreshwa kandi mukurinda neza hemoglobine mugukonjesha;catholyte, ikoreshwa muri IEF / 2-D gel electrophorei.
Glial selile umurongo ukomoka kuri neurotrophique (GDNF) nikintu gikomeye cyangiza ikoreshwa rya Ethanol no gusubira inyuma, kandi imbeba za GDNF heterozygous knockout zerekana ko zongerewe ibihembo kuri Ethanol kandi zikoresha Ethanol nyinshi nyuma yigihe cyo kwifata kuruta imyanda yabo yo mu gasozi.Hano, twagerageje niba Ethanol ihindura imvugo ya GDNF mukarere ka tegmental ya ventrale (VTA; urubuga rwa GDNF rwibikorwa) na / cyangwa nucleus accumbens (NAc; isoko nyamukuru ya GDNF), kandi niba aribyo, menya uruhare rwibintu bikura bikura. mugutunganya ikoreshwa rya Ethanol.Imiyoborere itunganijwe ya Ethanol yongereye imvugo ya GDNF hamwe na poroteyine muri VTA, ariko ntabwo ari NAc.Byongeye kandi, urwego rwa GDNF rwazamutse nyuma yigihe cyo kunywa Ethanol mu mbeba zanyweye Ethanol mugihe kimwe cyo guhitamo amacupa abiri mugihe cyicyumweru 1, ariko ntabwo ari ibyumweru 7.Kwamburwa nyuma yibyumweru 7 byo gufata Ethanol birenze urugero byagabanije urwego rwa GDNF, mugihe igihe gito cyo kunywa Ethanol igihe gito nyuma yo kwamburwa cyagengaga imvugo ya GDNF.Icy'ingenzi, gukubita GDNF muri VTA ukoresheje adenovirus yerekana umusatsi mugufi RNA byoroheje kwiyongera kwa kunywa Ethanol n'imbeba za Ethanol-naïve, ariko ntabwo byakozwe nimbeba zifite amateka yo kunywa cyane Ethanol.Ibisubizo byerekana ko mugihe cyambere cyo kunywa Ethanol, GDNF muri VTA yiyongera kandi ikarinda iterambere ryokunywa Ethanol ikabije.Nyamara, ibintu byo gukura birinda Ethanol birasenyuka nyuma yo gufata Ethanol ikabije no kuyikuramo, bikaviramo kunywa Ethanol bikabije.
