Ibicuruzwa

Acide ya Benzoic, 2 - [ Gukora nkibibanziriza cyangwa hagati ya synthesis ya molekile zitandukanye.Imiterere yihariye ya chimique, igizwe na ester ya benzoic acide ihujwe nitsinda rya amino na nitro, itanga amahirwe yo guhindura byinshi hamwe na derivatisation yo guteza imbere imiti mishya.Abashinzwe imiti barashobora gukoresha iyi nteruro kugirango bamenyekanishe imiterere itandukanye mu bakandida b’ibiyobyabwenge kandi bagenzure imiterere-yimikorere (SAR) kugirango bongere imiti yabo.Imikorere ya ester irashobora guhitamo hydrolyz kugirango itange aside irike ya karubike, ishobora noneho kuba inyubako zinyuranye zigamije iterambere ryibiyobyabwenge.Amatsinda ya amino na nitro, azwiho ibikorwa by’ibinyabuzima, arashobora gufasha mu iterambere ry’imiti ifite imiti igabanya ubukana, imiti igabanya ubukana, cyangwa imiti igabanya ubukana.Itsinda rya Carboxylate ester rishobora gukora nkitsinda ririnda imirimo ya aside, ikabarinda mugihe cyo guhindura imiti itandukanye.Amatsinda ya amino na nitro arashobora kuba nk'imyuka idahwitse kugirango irusheho gukomokaho cyangwa guhuza ibisubizo, bigafasha guhuza molekile zikomeye.Ubwinshi bwuru ruganda nkibikoresho byo gutangira cyangwa hagati bituma bigira agaciro kubashakashatsi ba chimique bagize uruhare muguhuza imiti myiza, imiti y’ubuhinzi, cyangwa ibikoresho byihariye.Ni ngombwa kumenya ko nubwo imiterere y’imiti y’uruganda yerekana ko ishobora gukoreshwa, ubushakashatsi n’isuzuma ni ngombwa mbere yimikoreshereze yihariye irashobora gushirwaho byuzuye.Ubushakashatsi bwimbitse, harimo gupima ibinyabuzima no gusuzuma uburozi, bugomba gukorwa kugira ngo bwumve imiterere y’umutekano no kumenya niba bukwiye mu guteza imbere ibiyobyabwenge.Byongeye kandi, ubushobozi bwacyo bwogukora hamwe nimbogamizi bigomba gushakishwa hifashishijwe ubushakashatsi bwimbitse bwa synthesis.Mu ncamake, aside benzoic, 2 - [ synthesis.Imiterere yihariye yimiti itanga amahirwe yo guhindura no kuyikomokaho, ishobora gushakishwa mugutezimbere ibiyobyabwenge cyangwa synthesis ya molekile igoye.Nyamara, ubushakashatsi nubushakashatsi birakenewe kugirango dusobanukirwe neza nibishobora gukoreshwa hamwe nimbogamizi muriyi nzego.