Ibicuruzwa

Biofilm igizwe na selile ya bagiteri ikomatanyirijwe hamwe na materique idasanzwe.Poly-beta (1,6) -N-acetyl-d-glucosamine (PNAG) ni igice kinini cya matrix ya biofilm muri bagiteri zitandukanye za phylogeneque.Muri ubu bushakashatsi twasesenguye imiterere yumubiri nubumara bya matrike ya PNAG muri biofilm ikorerwa muri vitro na gram-negative porcine respiratory pathogen Actinobacillus pleuropneumoniae hamwe na gram-positif nziza yibikoresho bifitanye isano na virusi yitwa Staphylococcus epidermidis.Ingaruka za PNAG kumazi menshi yagenwe mugupima igipimo cyo kwanduza amazi binyuze muri biofilm yatewe mumashanyarazi ya centrifugal.Igipimo cyo kwanduza amazi cyari hejuru cyane muri biofilm yatewe imbere ya enzyme ikwirakwiza PNAG yangiza B kuruta iyo muri biofilm yatewe idafite enzyme, byerekana ko PNAG igabanya umuvuduko mwinshi w'amazi.PNAG kandi yahagaritse gutwara transport ya quaternary ammonium compound cetylpyridinium chloride (CPC) ikoresheje biofilm.Guhambira CPC kuri biofilm byongeye kubuza kwanduza amazi no guhagarika ubwikorezi bwa azo dye Allura umutuku.Bioactive CPC yakuwe neza muri biofilm ivura hamwe na chloride 1 M ya sodium.Ufatiye hamwe, ibyagaragajwe byerekana ko CPC ikora neza na matrike ya PNAG kandi igahindura imiterere yumubiri nubumara.Ibisubizo byacu byerekana ko PNAG igira uruhare runini mugucunga imiterere yimiterere ya biofilm kandi ishobora kugira uruhare mubindi bikorwa bifitanye isano na biofilm nko kurwanya biocide.