Ibicuruzwa

Hashingiwe kuri ATP adenine, hateguwe urukurikirane rw'ibikomoka kuri adenine na purine kandi bipimwa ku bushobozi bwabo bwo guhagarika ubwoko butandukanye bwa kinase.Habayeho ubushakashatsi buke butohoza ubushobozi bwa cosubstrate ikomoka kuri kinase inhibitor kubindi kinase kuruta CDK.Igishushanyo mbonera cyacu cyahujije sisitemu ya purine kuva cosubstrate ya mbere ya ATP na fenyl moieties kugirango tumenye imikoranire ishoboka n'uturere dutandukanye twa ATP ihuza urubuga muri protein kinase nyinshi ziterwa n'indwara.Habayeho gukubitwa inshuro nyinshi kubintu byasuzumwe, byatumye tugera ku mwanzuro w'uko ibice bivangavanze bishobora kwerekana ko ari ibikoresho by'igikoresho cy'igiciro cyo gusuzuma isano no guhitamo uburyo butandukanye bwa kinase.