Ibicuruzwa

5,6-Dihydro-3- (4-morpholinyl) -1- [4- muri chimie yubuvuzi no kuvumbura ibiyobyabwenge.Dore ibisobanuro byerekana imikoreshereze yamagambo agera kuri 300.DMPHP izwiho ubushobozi bwayo nkimbaraga zikomeye kandi zihitamo inzitizi zimwe na zimwe zakira mumubiri wumuntu.Imwe mubikorwa byayo byibanze ni murwego rwa kinase kubuza.Kinase ni imisemburo igira uruhare runini munzira zerekana ibimenyetso kandi akenshi zigira uruhare mu ndwara zitandukanye, harimo na kanseri.DMPHP yasanze ihitamo guhitamo kinase yihariye, bityo igahagarika ibimenyetso byerekana ibimenyetso byerekana uruhare mu gutera indwara.Ibi bituma iba umukandida utanga ikizere cyo guteza imbere imiti igamije kurwanya indwara zitandukanye, harimo kanseri, gutwika, hamwe n’indwara zifata ubwonko.Ikindi kandi, DMPHP yerekanye ubushobozi mu rwego rwo kurwanya inflammatory na immunomodulatory.Gutwika nigisubizo gisanzwe cyumubiri kwandura cyangwa gukomeretsa ariko birashobora kuba karande kandi bigatera indwara zitandukanye.DMPHP yerekanye ubushobozi bwo guhagarika inzira zimwe na zimwe zitera inflammatory, kugabanya umusaruro wabunzi batera umuriro.Uyu mutungo ukora igikoresho cyingirakamaro mugutezimbere imiti igabanya ubukana, ifasha mukuvura indwara nka rubagimpande ya rubagimpande, indwara zifata amara, na asima. .Ububabare budashira nikibazo gikomeye cyubuzima, kandi uburyo bwo kuvura burigihe bufite aho bugarukira cyangwa ingaruka zitifuzwa.DMPHP yerekanye ingaruka zidasanzwe mu bushakashatsi bwibanze, byerekana ubushobozi bwayo nk'ubuvuzi bushya bwo kuvura ububabare.Muguhindura reseptor na neurotransmitter zifite uruhare mukwumva ububabare, DMPHP irashobora gutanga ubundi buryo bwo gucunga ububabare hamwe ningaruka zishobora kuba nkeya.Ikindi kandi, DMPHP yerekanye amasezerano mubijyanye na sisitemu yo hagati ya CNS).Indwara zifata ubwonko nk'indwara ya Alzheimer n'indwara ya Parkinson zirimo uburyo bugoye no kugabanya imiti itandukanye ya reseptor na enzymes mu bwonko.DMPHP yizwe kubushobozi bwayo nka neuroprotective agent ndetse nubushobozi bwayo bwo kongera imikorere yubwenge.Mu kwibasira ibyakiriwe n'inzira zifite uruhare mu ihungabana rya neurodegenerative, DMPHP isezeranya nk'ubuvuzi bwo kuvura ibi bihe bitoroshye. Mu gusoza, 5,6-Dihydro-3- (4-morpholinyl) -1- [4- (2-oxo- 1-piperidinyl) phenyl] -2 (1H) -pyridinone (DMPHP) nuruvange rwinshi hamwe nibishobora gukoreshwa muguhagarika kinase, ibikorwa byo kurwanya inflammatory, analgesia, na neuroprotection.Ubushobozi bwayo bwo guhitamo imisemburo yihariye hamwe niyakira byinjira munzira zindwara bituma iba umukandida ushimishije kuvumbura imiti no kuvura imiti.Ubundi bushakashatsi niterambere birashobora kuvumbura imikoreshereze yinyongera no guhuza imiterere yabyo kubimenyetso byihariye.