Ibicuruzwa

. (4R-cis) .Imiterere yihariye hamwe nitsinda ryimikorere ikora bifite agaciro kubikorwa bitandukanye.Mu nganda zimiti, iyi nteruro irashobora kuba inyubako yubaka cyangwa hagati muguhuza imiti itandukanye.Itsinda rya chloromethyl, hamwe nimpeta ya dioxane, ritanga amahirwe yo gukomeza gukoreshwa no gukora kugirango habeho molekile zifite imiti ya farumasi.Abahanga mu bya shimi barashobora guhindura iki kigo kugirango bamenyekanishe ibintu byihariye cyangwa imikorere, bishobora kuzamura ibiyobyabwenge, bigatera imbaraga zo gukemura, cyangwa kongera imbaraga za metabolike. Byongeye kandi, itsinda rya tert-butyl ester ritanga uburinzi kumikorere ya aside ya karubone mugihe cyo guhindura ibintu bitandukanye.Irashobora gukora nk'itsinda ririnda, kwemeza imikorere ya aside ikomeza kuba nziza imbere ya reagent reaction cyangwa reaction.Iyi ngingo ni ingirakamaro cyane cyane muri synthesse ya multistep, aho andi matsinda yimikorere ashobora gukenera gukoreshwa bitagize ingaruka kumyuka ya acide karubike.Mu bikorwa byubuhinzi, (4R-cis) -6-Chloromethyl-2,2-dimethyl-1,3-dioxane -4-acetike Acide tert-Butyl Ester irashobora kubona akamaro mugutezimbere ibyatsi cyangwa imiti yica udukoko.Imiterere yikomatanya itanga amahirwe yo guhindura kugirango ikore ibikomoka hamwe nintego yihariye yo guhitamo hamwe nuburozi bwuburozi.Gukoresha ibice nkibi birashobora kugira uruhare mugutezimbere ibisubizo byiza kandi bitangiza ibidukikije mukurinda ibihingwa.Mu sintezike kama, iyi compound irashobora kuba reagent itandukanye yo gukora molekile zigoye.Impeta ya dioxane, hamwe nitsinda rya chloromethyl, irashobora guhura nuburyo butandukanye, bigatuma hashyirwaho andi matsinda akora cyangwa sisitemu yimpeta.Byongeye kandi, itsinda rya tert-butyl ester rishobora gukurwaho, bikerekana imikorere ya acide karubike kugirango ikoreshwe.Uru ruganda rushobora gukoreshwa mukubaka ibicuruzwa karemano, abahuza imiti, cyangwa ibindi bintu byingirakamaro kama.Ni ngombwa kwerekana ko uburyo bwihariye nogukoresha (4R-cis) -6-Chloromethyl-2,2-dimethyl-1 , 3-dioxane-4-acetike Acide tert-Butyl Ester irashobora gutandukana bitewe nintego igenewe, imiterere yimikorere, cyangwa ibisubizo byifuzwa.Abahanga n'abashakashatsi muri za kaminuza, inganda, cyangwa amashyirahamwe ya leta barashobora gushakisha ubushobozi bwayo mubushakashatsi bwa molekile, iterambere ryiterambere, cyangwa guhuza ibitekerezo. Mugusoza, (4R-cis) -6-Chloromethyl-2,2-dimethyl-1,3-dioxane -4-acetike Acide tert-Butyl Ester nuruvange rwinshi hamwe nibisabwa muri farumasi, ubuhinzi-mwimerere, hamwe na synthesis organique.Imiterere yihariye yimiterere hamwe nitsinda ryimikorere itanga amahirwe yo guhindura imiti itandukanye, bigafasha iterambere ryimiti mishya, ubuhinzi-mwimerere, cyangwa ibinyabuzima bifite agaciro.Ubundi bushakashatsi nubushakashatsi birashobora kwerekana izindi nyungu cyangwa inyungu zuru ruganda mubice bitandukanye bya siyansi ninganda.