4-Amino-1 - ((2R, 4S, 5R) -4-hydroxy-5- (hydroxymethyl) tetrahydrofuran-2-yl) pyrimidin-2 (1H) -umuntu umwe Cas: 951-77-9
Umubare wa Cataloge: | XD90580 |
Cas: | 951-77-9 |
Inzira ya molekulari: | C9H13N3O4 |
Uburemere bwa molekile: | 227.22 |
Kuboneka: | Mububiko |
Igiciro: | |
Gutegura: | 1g USD10 |
Igipapuro kinini: | Saba Amagambo |
Kugaragaza ibicuruzwa
Kugaragara | Ifu ya kirisiti yera |
Suzuma | 99% |
Ingingo yo gushonga | 196 ° C - 200 ° C. |
Thymidine fosifora (TP, EC 2.4.2.4) yamenye imiterere ya substrate ifite umwihariko wo hejuru, ikoresheje ibishingwe hamwe na ribosyl moieties.Gusimbuza 3'-OH ya thymidine byagize uruhare runini mubikorwa byayo bya catalitiki hamwe na TP.Guhindura nucleoside ya pyrimidine hamwe na moieties yahinduwe muburyo bwa 1-fosifate byari bibi.Ibikorwa byo gusiga amatsinda byagabanutse hamwe no kwiyongera kwimpumuro nziza ya pyrimidine, kubera ingorane ziyongereye muguhindura ibice na acide amine yaho ikorera kurubuga rukora.Gusimbuza amatsinda yimikorere ya 3 'na 5' byakunze kugabanya igipimo cyibisubizo hamwe nijanisha rihinduka hamwe na TP.By'umwihariko ribosyl 3 'hydroxyl groupe yari ingirakamaro muburyo bwo guhuza substrate na enzyme.Isuzuma rya kinetic ryerekanaga neza K (m) hamwe na V (max) agaciro gake mugusimbuza itsinda rya 3 'hydroxyl hamwe na hydrogen.