Ibicuruzwa

4- (4-Fluorophenyl) -6-Isopropyl-2 - gusaba mubushakashatsi bwa farumasi no guteza imbere ibiyobyabwenge.Yashyizwe mubikorwa nkibikomoka kuri pyrimidine hamwe nitsinda rya formyl ryometse kuri atome ya karubone ya 5, hamwe na 4-fluorophenyl hamwe nitsinda rya isopropyl ryometse kuri atome ya karubone ya 4 na 6. Kimwe mubikorwa byingenzi bya FIMPA biri murwego rwa ubushakashatsi bwa kanseri.Ibikomoka kuri Pyrimidine byakozweho ubushakashatsi bwimbitse kubintu birwanya antitumor, kandi FIMPA yerekana ubushobozi nkumuti urwanya antikanseri.Imiterere yimiterere ituma iba umukandida utanga ikizere cyo guhagarika imisemburo yingenzi cyangwa reseptor zigira uruhare mu mikurire yikibyimba no gutera imbere.Abashakashatsi barashobora guhindura imiterere ya FIMPA kugirango barusheho kongera imbaraga, guhitamo, hamwe n’imiti ya farumasi kugira ngo barusheho kuvura kanseri neza.Ikindi kandi, FIMPA irashobora kandi gukora nka molekulike yo guteza imbere abakandida b’ibiyobyabwenge byibasira izindi ndwara.Imiterere yihariye yemerera guhuza amatsinda atandukanye akora, ashobora kugira uruhare runini muguhuza intego yihariye ya molekile.Ubu buryo bwinshi butuma FIMPA igikoresho cyingirakamaro muri chimie yubuvuzi mugutezimbere imiti ivura indwara zitandukanye nkindwara zifata ubwonko cyangwa indwara zanduza. Usibye kuba ishobora kuvura, FIMPA irashobora gukoreshwa muguhuza ibindi bintu kama kama kama.Amatsinda yayo akora neza, nka formyl na sulfonyl, arashobora kuba urubuga rwo guhindura imiti.Abashakashatsi barashobora gukoresha FIMPA nk'ibikoresho bitangira cyangwa ibice bigereranijwe kugirango babone ibikomoka ku binyabuzima bitandukanye, bishobora kugenzurwa kubikorwa byabo byibinyabuzima cyangwa bigakoreshwa nkibice byubaka kugirango habeho synthesis ya molekile zigoye. Muri rusange, 4- (4-Fluorophenyl) -6-Isopropyl -2 -Imiterere yihariye hamwe nitsinda ryimikorere bituma iba igikoresho cyingenzi cyo gutegura abakandida bashya ibiyobyabwenge cyangwa guhuza ibinyabuzima bigoye.Ubundi bushakashatsi no kunoza imitungo ya FIMPA birashobora gutuma havumburwa imiti ivura udushya kandi ikagira uruhare mu iterambere rya chimie miti.