Ibicuruzwa

(3S) -3- [4 -Bikunze gukoreshwa mubijyanye nubushakashatsi bwa farumasi niterambere bitewe nuburyo bushobora kuvura.Bimwe mubikorwa byingenzi byuru ruganda biri mubushobozi bwayo bwo guhura nibinyabuzima bitandukanye, imisemburo, cyangwa proteyine mumubiri wumuntu.Iyi mikoranire irashobora kuganisha ku guhindura inzira yihariye ya biohimiki, bishobora kuvamo ingaruka zo kuvura.Abashakashatsi bakunze gukora ubushakashatsi ku ruhare rw’uru ruganda nk'umuntu ushobora kuba umukandida w’ibiyobyabwenge ku ndwara zitandukanye. Ibintu bigize imiterere y’urwo ruganda, harimo kuba hari impeta ya tetrahydrofuran hamwe n’itsinda rya fenyl ryasimbuwe, bigira uruhare mu miterere yihariye ya farumasi.Itsinda rya fenyl ritanga imikoranire ya hydrophobique, ishobora kugira ingaruka kumyunyungugu no guhuza poroteyine.Ikigeretse kuri ibyo, kuba hari atome ya bromine na chlorine mu mpeta ya fenyl yongerera ibintu byinshi imiterere y’imiti y’imiti, bishobora gutuma habaho imikoranire yihariye na molekile y’ibinyabuzima igamije. Guhuza no guhitamo kwa (3S) -3- [4 - [(5) -Bromo-2-chlorophenyl) methyl] phenoxy] tetrahydrofuran kubakira cyangwa imisemburo yihariye igena uburyo bwo kuvura.Kubera iyo mpamvu, abashakashatsi bakora iperereza ku ngaruka zabyo ku ntego zitandukanye za molekuline, nk'iyakira mu kugira uruhare mu gutwika, kanseri, cyangwa indwara zo mu mitsi yo hagati.Ubushakashatsi butandukanye bwibinyabuzima hamwe nicyitegererezo cyinyamanswa birashobora gukoreshwa kugirango hamenyekane uburyo bwibikorwa, kwinjiza, gukwirakwiza, metabolism, no gusohoka.Aya makuru ni ingenzi mu gusuzuma imiti ya farumasi no gusobanukirwa uburyo ikorana numubiri wumuntu.Nyamara, ni ngombwa kumenya ko (3S) -3- [4 - [(5-Bromo-2-chlorophenyl) methyl] phenoxy] tetrahydrofuran iracyari mubyiciro byubushakashatsi, kandi nibishobora gukoreshwa muburyo bwo kuvura ntiburacukumburwa neza.Ubushakashatsi bwagutse, harimo n’ibizamini by’amavuriro ku bantu, byaba ngombwa kugira ngo hamenyekane umutekano n’akamaro kabwo mbere yuko bisuzumwa kugira ngo bikoreshe imiti. Mu gusoza, (3S) -3- [4 - [(5-Bromo-2-chlorophenyl) methyl ] phenoxy] tetrahydrofuran kuri ubu irimo gukorwaho iperereza kubishobora gukoreshwa muburyo bwo kuvura imiti.Imiterere yihariye ya chimique igira uruhare mubikorwa byayo hamwe nintego yihariye yibinyabuzima, gufungura uburyo bwo guteza imbere imiti ivura udushya.Nyamara, ubushakashatsi nisuzuma birakenewe kugirango hamenyekane ubushobozi bwukuri nkibintu bivura.