Ibicuruzwa

3-Methyl-7- (2-butyn-1-yl) -8-bromoxanthine ni imiti ivanga umuryango wa xanthine.Ibikomoka kuri Xanthine byizwe cyane kandi bizwi muburyo butandukanye bwo gukoresha, cyane cyane mubijyanye na farumasi. Kimwe mubikorwa byingenzi bya 3-Methyl-7- (2-butyn-1-yl) -8-bromoxanthine nibishobora gukoreshwa nk'umuti wo kuvura indwara z'ubuhumekero nka asima n'indwara idakira ifata ibihaha (COPD).Ibikomoka kuri Xanthine, harimo na theophylline, bimaze igihe kinini bikoreshwa mu buvuzi bw’ubuhumekero kubera imiterere ya bronchodilatory na anti-inflammatory.Izi nteruro zikora mukworohereza imitsi yoroshye mumyuka yumuyaga no kugabanya gucana, bityo bikanoza imikorere yo guhumeka. Kwiyongera kwa atome ya bromine kumwanya wa 8 wimpeta ya xanthine muri 3-Methyl-7- (2-butyn-1-yl) -8-bromoxanthine irashobora kongera ingaruka za bronchodilatory ugereranije nibindi bikomoka kuri xanthine.Gusimbuza Bromine mubintu bisa byagaragaye ko byongera imbaraga nigihe cyibikorwa.Kubwibyo, uru ruganda rushobora kugira ubushobozi nkuburyo bwiza kandi buramba bwa bronchodilator kumiterere yubuhumekero.Ikindi kandi, xanthine nayo yakozweho ubushakashatsi kubijyanye na neuroprotective.Bagaragaje ingaruka za antioxydeant na anti-inflammatory, hamwe nubushobozi bwo kongera amaraso yubwonko no kunoza imikorere yubwenge.Iyi mitungo ituma baba abakandida bashimishije kuburwayi bwa neurodegenerative nkindwara za Alzheimer na Parkinson. Usibye gukoresha imiti, 3-Methyl-7- (2-butyn-1-yl) -8-bromoxanthine irashobora kandi gukoreshwa mubushakashatsi bwa siyansi.Ibikomoka kuri Xanthine bikunze gukoreshwa nkibikoresho bya biohimiki byo kwiga reseptor ya adenosine na enzymes za fosifori.Izi mvange zirashobora gukora nka ligande yatoranijwe cyangwa inhibitor, zifasha mugukora iperereza ryimikorere ya molekile yihariye n'inzira. Guhindura no guhindura 3-Methyl-7- (2-butyn-1-yl) -8-bromoxanthine birashobora guhuzwa kugirango bikomeze Hindura imitungo yacyo kubikorwa byihariye.Imiti itandukanye yimiti, nko gusimbuza, kongeramo, no guhuza reaction, irashobora gukoreshwa mugutangiza amatsinda akora cyangwa guhindura imiterere yibanze.Izi mpinduka zirashobora kuzamura ibikorwa bya farumasi cyangwa bigafasha iterambere ryibikomoka hamwe no guhitamo neza no guhitamo bioavailable.Mu gusoza, 3-Methyl-7- (2-butyn-1-yl) -8-bromoxanthine ifite amahirwe menshi yo gukoresha mubuvuzi bwubuhumekero , neuroprotection, hamwe nubushakashatsi bwibinyabuzima.Ingaruka zayo ziterwa na bronchodilatory zituma iba umukandida utanga ikizere cyo kuvura indwara zubuhumekero, kandi imiterere ya neuroprotective ishobora kwerekana ko ikoreshwa mu ndwara zifata ubwonko.Ubundi bushakashatsi niterambere bizakenerwa gushakisha byimazeyo no gukoresha inyungu zuru ruganda mubice bitandukanye byubuvuzi nubumenyi.