Ibicuruzwa

(2S) -1-.Uru ruganda, ruzwi kandi nka (2S) -2-Chloroacetylpyrrolidine-1-karubonitrile, rufite imiterere yihariye ituma igira agaciro mugutezimbere imiti mishya hamwe no guhuza molekile zigoye. Kimwe mubishobora gukoreshwa (2S) -1- .Itsinda ryaryo rya chloroacetyl hamwe na cyano (carboneitrile) bituma hashyirwaho andi matsinda yimikorere ndetse no gushiraho imiti mishya.Ubu buryo bwinshi butuma bugira akamaro muguhuza ibice bitandukanye, harimo imiti, imiti y’ubuhinzi, n’imiti yihariye.Mu rwego rwa chimie chimique, (2S) -1- (Chloroacetyl) -2-pyrrolidinecarbonitrile irashobora gushakishwa nka farumasi cyangwa imiterere. motif mugushushanya ibiyobyabwenge.Imiterere yihariye hamwe nitsinda ryimikorere irashobora gukorana nintego yihariye yibinyabuzima, nka enzymes, reseptors, cyangwa proteyine, bityo bikagira ingaruka kubikorwa byabo.Muguhindura uturere dutandukanye twa molekile, abashakashatsi barashobora kwiga no kunoza imiterere yimiti ya farumasi, birashoboka ko biganisha kumajyambere yubuvuzi bushya bwo kuvura. Byongeye kandi, (2S) -1- (Chloroacetyl) -2-pyrrolidinecarbonitrile irashobora kuba igikoresho cyingenzi mubinyabuzima ubushakashatsi.Irashobora gukoreshwa mugushiraho intego za poroteyine cyangwa molekile zinyungu, zitanga uburyo bwo kwiga imyitwarire n'imikoranire yabo muri sisitemu y'ibinyabuzima.Muguhuza ibirango cyangwa ibirango bikwiye kuriyi nteruro, abashakashatsi barashobora gukurikirana ikwirakwizwa ryayo nuburyo bwo guhuza, bikagira uruhare mugusobanukirwa neza inzira yibinyabuzima. Byongeye kandi, (2S) -1- (Chloroacetyl) -2-pyrrolidinecarbonitrile ya chiral, yerekanwe na ( 2S) kumenyekanisha, ifungura ibishoboka kugirango ikoreshwe muri synthesis idasanzwe.Imvange ya Chiral ifite ibishushanyo bitandukanye bya atome muburyo bwayo, bitanga ubushobozi bwo gukora ibice bya enantiopure, ari molekile zibaho murimwe gusa muburyo bubiri bw'ishusho.Uyu mutungo ufite agaciro kanini mubuvumbuzi bwibiyobyabwenge, kuko imiti ya enantiopure irashobora kwerekana ibikorwa bya farumasi byongerewe imbaraga kandi bikagabanya ingaruka mbi.Mu ncamake, (2S) -1- (Chloroacetyl) -2-pyrrolidinecarbonitrile nuruvange rwinshi hamwe nibisabwa byinshi mubushakashatsi bwa farumasi na organic synthesis.Ifite ubushobozi bwo gukora nk'urwego rwo kubaka synthesis ya molekile igoye, nk'intangiriro yo guteza imbere ibiyobyabwenge, kandi nk'igikoresho cyo gukora ubushakashatsi ku binyabuzima na biologiya.Ubundi bushakashatsi no gukora iperereza kumitungo yabyo bizadufasha kurushaho gusobanukirwa nibishobora gukoreshwa kandi birashobora gutuma havumburwa imiti ivura imiti.