Ibicuruzwa

Hakozwe aptasensor ikora neza aho graphene oxyde (GO) yakoreshwaga nk'ikimenyetso cyerekana amashanyarazi yerekana amashanyarazi hamwe na electrochemiluminescence (ECL).Aptasensor yahimbwe no kwiyegeranya na ECL iperereza rya adenosine triphosphate ihuza aptamer (ABA) yashushanyije hamwe na Ru complex (Ru (bpy) 3 (2+) ikomoka) hejuru ya zahabu ya nanoparticle (AuNP) yahinduye karubone yikirahure; electrode (GCE).ABA yimuwe kuri AuNP yahinduwe GCE irashobora kwamamaza cyane GO kubera imikoranire ikomeye π-π hagati ya ABA na graphene oxyde;ECL kuzimya ikigo cya Ru noneho bibaho kubera guhererekanya ingufu no guhererekanya electron, hamwe no kwiyongera kwinshi kwimurwa rya electron (Ret) ya electrode.Mugihe imbere yintego ya adenosine triphosphate (ATP), ABA ihitamo gushinga ibinyabuzima bya bioaffinity ABA-ATP, bifite aho bihurira na okiside ya graphene kandi bigatuma okiside ya graphene itaba hejuru ya electrode, bityo bikemerera kongera ibimenyetso bya ECL, kandi, ifatanije no kugabanuka kwa Ret.Kubera imikorere ya ECL yo kuzimya cyane, imiterere idasanzwe, hamwe nibikoresho bya elegitoronike ya graphene oxyde, ubukana bwa Ret na ECL hamwe na logarithm yibitekerezo bya ATP byari umurongo mugari kuva kuri 10 pM kugeza 10 nM hamwe na ultra-low detection ya 6.7 pM kugeza kuri 4.8 pM.Icyifuzo cya aptasensor cyerekanaga imyororokere myiza, itajegajega, hamwe no guhitamo kwiza, kandi ATP ishobora gutandukanywa neza na byo.Ikigaragara cyane, ubu buryo bwiza bwa ECL aptasensor bushingiye kuri GO ikora nkibipimo byerekana amashanyarazi na ECL nibimenyetso rusange kandi birashobora kwaguka byoroshye mubindi bintu bihuza ibinyabuzima.