Ibicuruzwa

2-Pyrrolidinecarboxamide, 1- (2-chloroacetyl) -, (2S) - ni uruganda rufite porogaramu zitandukanye mubijyanye na chimie organic nubushakashatsi bwa farumasi.Uru ruganda, ruzwi kandi nka (2S) -2-Pyrrolidinecarboxamido-2-aside ya chloroacetic aside amide, yerekana imiterere yimiterere ituma bikwiranye nuburyo bumwe na bumwe bwimiti nubushakashatsi bwibinyabuzima. Muri synthesis organique, (2S) -2-Pyrrolidinecarboxamido-2-chloroacetic aside amide irashobora gukoreshwa nkibintu bitangira cyangwa hagati muguhuza molekile zigoye.Imiterere ya chiral, hamwe nizina (2S), yerekana ko ifite gahunda yihariye yibice bitatu bya atome zishobora kugira ingaruka kuri stereochemie nimiterere yibikomokaho.Uyu mutungo uhesha agaciro mugushushanya no gukora imiti mishya hamwe n’ibikoresho bya farumasi.Mu nganda zimiti, (2S) -2-Pyrrolidinecarboxamido-2-chloroacetic acide amide yizwe kubushobozi bwayo nkibuza imisemburo cyangwa proteyine zigira uruhare inzira yihariye y'ibinyabuzima.Ubushakashatsi bumwe bwibanze ku kuyishyira mu bikorwa nk'ibuza poroteyine zimwe na zimwe, ari zo misemburo igira uruhare mu bikorwa bitandukanye bya fiyologiki.Muguhitamo guhitamo no guhagarika izo poroteyine, ingaruka zijyanye no kuvura zirashobora kugerwaho. Byongeye kandi, (2S) -2-Pyrrolidinecarboxamido-2-acide acide chloroacetic amide irashobora kuba intangiriro yo guhuza synthesis ya peptide cyangwa kwigana.Izi molekile zirashobora kwigana imiterere n'imikorere ya peptide isanzwe ibaho, bityo bikagira ingaruka kubinyabuzima cyangwa ibikorwa byihariye.Ibigereranyo nk'ibi birashobora kugira uruhare runini mugutezimbere imiti yo kuvura indwara zitandukanye, harimo kanseri, indwara ziterwa na metabolike, hamwe n’imiterere y’imitsi. Ni ngombwa kumenya ko (2S) -2-Pyrrolidinecarboxamido-2-aside aside ya chloroacetic amide ikoreshwa cyane cyane mubushakashatsi bwa laboratoire kandi ntabwo byemewe gukoreshwa mubuvuzi.Ubu buryo bwo kuvura bushobora gukoreshwa buracyashakishwa, kandi haracyakenewe ubundi bushakashatsi kugira ngo hamenyekane umutekano wabwo n’ingirakamaro mu bantu. Mu gusoza, (2S) -2-Pyrrolidinecarboxamido-2-acide acide chloroacetic amide ni uruvange hamwe nuburyo butandukanye muri synthesis organique na ubushakashatsi mu bya farumasi.Imiterere ya chiral hamwe nubushobozi bwo guhagarika imisemburo cyangwa proteyine zihariye bigira agaciro mugutezimbere imiti mishya hamwe nuburyo bwo kuvura.Mugihe ikoreshwa ryubushakashatsi bwa laboratoire ryerekana amasezerano, irindi perereza rirakenewe kugirango wumve neza ubushobozi bwaryo mubuvuzi.