Vancomycin hydrochloride CAS: 1404-93-9 99% Umweru cyangwa umutuku kugeza ifu yijimye
Umubare wa Cataloge | XD90370 |
izina RY'IGICURUZWA | Vancomycin hydrochloride |
URUBANZA | 1404-93-9 |
Inzira ya molekulari | C66H75Cl2N9O24.HCl |
Uburemere bwa molekile | 1485.72 |
Ibisobanuro birambuye | 2 kugeza 8 ° C. |
Amategeko agenga ibiciro | 29419000 |
Kugaragaza ibicuruzwa
Amazi | NMT 5.0% |
Ibyuma biremereye | NMT 30ppm |
pH | 2.5-4.5 |
Endotoxine ya bagiteri | NMT 0.33EU / mg ya Vancomycin |
Igisubizo cyumuti | Biragaragara |
Suzuma | 99% |
Vancomycin B. | NLT 900ug / mg |
Imipaka ya monodechlorovancomycin | NMT 4.7% |
Kugaragara | Umweru, hafi yera, cyangwa umutuku kugeza ifu yijimye |
Umubare w'abaturage banduye methicilline-wihanganira indwara ya Staphylococcus aureus uragenda wiyongera ku buryo butangaje.Kuvura neza byagize uruhare mu mateka ya débridement hakiri kare no kuyobora antibiotique.Ubu bushakashatsi bwakozwe hagamijwe kumenya neza uburyo bwo kuvura indwara zifatika mu kuvura indwara zanduye. Ikigeragezo giteganijwe cyakozwe ku bitaro byo ku rwego rwa I.Abarwayi banduye intoki bakiriye vancomycine yo mu maraso yinjira cyangwa yinjira muri cefazoline.Ibisubizo byakurikiranwe hakoreshejwe ubukana bwanduye, ibisubizo bikwiye byubuvuzi, hamwe nigihe cyo kumara.Ikiguzi-cyiza cyabazwe ukoresheje ikiguzi cyose kuri buri murwayi mumatsinda yombi.Isesengura mibare ryakozwe. Abarwayi mirongo ine na batandatu bariyandikishije mu bushakashatsi.24 ni bo batoranijwe kuri cefazoline (52.2 ku ijana) na 22 (47.8 ku ijana) kuri vancomycine.Nta tandukanyirizo ryibarurishamibare ryari hagati yikiguzi cyo kwivuza (p <0,20) cyangwa bivuze uburebure bwo kumara (p <0.18) betwee n amatsinda.Abarwayi batoranijwe kuri cefazolin bari bafite amafaranga menshi yo kwivuza ugereranije n’abarwayi batoranijwe na vancomycine (p <0.05).Abarwayi bafite ubwandu bukabije bafite amafaranga menshi yo kuvura (p <0.0001) kandi birebire bisobanura igihe cyo kumara (p = 0.0002).Hafi y’ubushakashatsi burangiye, byagaragaye ko indwara ya S. aureus yanduye methicilline y’abaturage mu bitaro by’intara y’abanditsi yavumbuwe ko ari 72 ku ijana, ibyo bikaba byaratumye ubushakashatsi burangira imburagihe n’inama y’isuzumamikorere kubera ibigo byinshi. kubuza gukomeza gutoranya.Ubuvuzi bukwiye bwo kuvura methicilline irwanya S. aureus ntabwo bwashyizweho neza.Nta tandukanyirizo ryibisubizo ukoresheje cefazolin na vancomycin nkumukozi wambere wumurongo wamenyekanye.