SYBR GREEN I Nucleic Acide Gel Stain Cas: 163795-75-3 99% Ikomeye
Umubare wa Cataloge | XD90236 |
izina RY'IGICURUZWA | SYBR GREEN I Nucleic Acide Gel Ikirangantego |
URUBANZA | 163795-75-3 |
Inzira ya molekulari | C32H37N4S |
Uburemere bwa molekile | 509.728 |
Ibisobanuro birambuye | -20 ° C. |
Kugaragaza ibicuruzwa
Kugaragara | Ifu yera |
Suzuma | 99% |
Flow cytometrie nuburyo bufatika bwo kuyobora muri vitro antimalarial sensitivite hamwe nubushobozi bwokoreshwa mubibuga.Twasuzumye muri vitro kwandura imiti irindwi irwanya malariya kumurima 40 mushya wa P. falciparum witandukanije hakoreshejwe uburyo bwa cytometrie (FCM), ibara rya LDH rishingiye kuri ELISA: DELI), hamwe nisesengura rya microscopique ryerekana iterambere.Kuri FCM, 184/280 (66%) isuzuma ryujuje ibisabwa kugirango umuntu yemererwe gusesengura, ugereranije na 166/280 (59%) kuri DELI.Hariho amasezerano meza hagati ya FCM na microscopi, mugihe DELI yakundaga kubyara igice kinini-ntarengwa cyo guhagarika (IC50s) kurusha FCM, hamwe kubogama muri rusange inshuro 2,2 (kugereranya Bland-Altman).Indangagaciro za artesunate na dihydroartemisinin zagize ingaruka cyane.Ubwiyongere bwa paradoxique bwibimenyetso cyane cyane bya mefloquine hamwe nibindi bifitanye isano nabyo byaranzwe cyane na DELI, byerekana ko ingaruka zitari nziza ku musaruro wa LDH zishobora kuba nyirabayazana.Gutakaza ibimenyetso bya FCM kubera kugarura cyangwa gukura buhoro byagaragaye mu mubare muto w'icyitegererezo.Ibisubizo byongereye imirimo yabanjirije ikoreshwa rya flux cytometrie kugirango hamenyekane kwandura antimalariya ukurikije umubare wintangarugero, ibiyobyabwenge, hamwe nubundi buryo.