Rapamycin yo muri Streptomyces hygroscopicus CAS: 53123-88-9 Ifu yera-yera cyangwa ifu ya kristalline
| Umubare wa Cataloge | XD90356 |
| izina RY'IGICURUZWA | Rapamycin yo muri Streptomyces hygroscopicus |
| URUBANZA | 53123-88-9 |
| Inzira ya molekulari | C51H79NO13 |
| Uburemere bwa molekile | 914.17 |
| Ibisobanuro birambuye | -20 ° C. |
| Amategeko agenga ibiciro | 2942000000 |
Kugaragaza ibicuruzwa
| Suzuma | 99% |
| Kugaragara | Ifu yera-yera cyangwa umuhondo wa kristaline |
Rapamycin, ibiyobyabwenge byagaragaye ko byongera ubuzima bwimbeba, bibuza intego yinzira ya rapamycin (TOR), inzira nini igenga imikurire ningirabuzimafatizo.Byaravuzwe ko rapamycin no kugabanya imirire (DR) byongerera igihe ubuzima binyuze muburyo bumwe / inzira.Twifashishije isesengura rya microarray, twagereranije transcriptome yumubiri wa adipose yera kuva imbeba zagaburiwe rapamycin cyangwa DR-diet mumezi 6.Isesengura ryinshi nubushyuhe bwa hotmap byerekanaga ko rapamycin nta ngaruka yagize kuri transcriptome ugereranije na DR.Kurugero, inyandiko esheshatu gusa zahinduwe cyane na rapamycin mugihe imbeba zagaburiwe DR zerekanye impinduka zikomeye mumyandikire irenga 1000.Twifashishije isesengura ryubwenge bwinzira, twasanze steosyte biosynthesis hamwe ninjyana ya circadian yerekana ibimenyetso byahinduwe cyane na DR.Ibyavuye mu bushakashatsi byerekana ko DR, ariko atari rapamycin, igira ingaruka ku nyandiko-mvugo ya tipusi ya adipose, byerekana ko ubwo buryo bubiri bwongera ubuzima binyuze mu nzira zitandukanye.
