Ibicuruzwa

R-PMPA, izwi kandi ku izina rya tenofovir disoproxil fumarate (TDF), ni imiti igabanya ubukana bwa virusi ikoreshwa cyane mu kuvura virusi itera SIDA (virusi itera SIDA) n'indwara ya hepatite B idakira (HBV).Ni prodrug yo mu kanwa ihindurwa muburyo bukora, tenofovir diphosphate, imbere mumubiri.R-PMPA ni mubyiciro byibiyobyabwenge byitwa nucleotide reverse transcriptase inhibitor (NRTIs).Ikora muguhagarika enzyme ya reverse transcriptase, ningirakamaro mu kwigana virusi itera sida na HBV.Muguhagarika iyi ntambwe yingenzi mugikorwa cyo kwigana virusi, R-PMPA ifasha kugabanya umutwaro wa virusi no kugabanya umuvuduko w’indwara.Iyo ikoreshwa mu kuvura virusi itera sida, R-PMPA ikunze gutegekwa mu rwego rwo kuvura imiti igabanya ubukana bwa virusi. (cART) gahunda.Itangwa hamwe nindi miti igabanya ubukana bwa virusi itandukanye yo mu byiciro bitandukanye byibiyobyabwenge kugirango yongere umusaruro kandi igabanye iterambere ry’imiti.Gahunda yihariye ya CART izaterwa nimpamvu z'abarwayi ku giti cyabo, nk'icyiciro cyo kwandura virusi itera sida, amateka yo kuvura mbere, ndetse n'ubuzima ubwo ari bwo bwose bwo mu buzima. Mu kuvura indwara zidakira HBV, R-PMPA ubusanzwe yandikirwa imiti imwe cyangwa ifatanije na indi miti igabanya ubukana.Igihe cyo kuvura gishobora gutandukana bitewe n'uburemere bw'ubwandu ndetse n'umuntu ku giti cye ku miti.Imiti ya R-PMPA izagenwa n'inzobere mu by'ubuzima ishingiye ku bintu nk'imikorere y'impyiko, imyaka, ibiro, ndetse no kuba hari ibyo ari byo byose ubundi buzima.Ni ngombwa gukurikiza amabwiriza yatanzwe yo kugabanya no kudahindura ibipimo utabanje kubaza abashinzwe ubuzima.R-PMPA muri rusange irihanganirwa, ariko nkimiti iyo ari yo yose, irashobora gutera ingaruka.Ingaruka zisanzwe zirimo isesemi, kuruka, impiswi, no kubabara umutwe.Rimwe na rimwe, R-PMPA irashobora gutera ingaruka mbi zikomeye, nko kudakora impyiko cyangwa gutakaza amagufwa yubunini.Gukurikirana buri gihe imikorere yimpyiko nubuzima bwamagufwa birasabwa mugihe cyo kuvura.Ni ngombwa gufata R-PMPA neza nkuko byateganijwe no kubahiriza gahunda yo kuvura buri gihe.Kubura dosiye cyangwa guhagarika kwivuza imburagihe birashobora gutuma habaho iterambere ryo kurwanya ibiyobyabwenge no kugabanya uburyo bwo kuvura.Mu ncamake, R-PMPA (tenofovir disoproxil fumarate) ni imiti igabanya ubukana bwa virusi ikoreshwa mu kuvura ubwandu bwa virusi itera sida n'indwara zidakira HBV.Ikora muguhagarika uburyo bwo kwigana virusi kandi ikoreshwa kenshi murwego rwo kuvura virusi itera sida.Gukurikiranira hafi no kubahiriza ubuvuzi nibyingenzi kugirango bigerweho neza.Kugisha inama ninzobere mu by'ubuzima ni ngombwa kugira ngo umenye gahunda iboneye yo kuvura no gukemura ingaruka zose zishobora kubaho.