Umunyu wa potasiline G potasiyumu CAS: 113-98-4 99% Ifu yera
| Umubare wa Cataloge | XD90351 |
| izina RY'IGICURUZWA | Umunyu wa potasiline G. |
| URUBANZA | 113-98-4 |
| Inzira ya molekulari | C16H17KN2O4S |
| Uburemere bwa molekile | 372.48 |
| Ibisobanuro birambuye | Ibidukikije |
| Amategeko agenga ibiciro | 29411000 |
Kugaragaza ibicuruzwa
| Gutakaza Kuma | <1.0% |
| Ibara ry'umuti | Ntabwo afite amabara menshi kurenza ubukana Y2 cyangwa YG2 yurwego rwerekana |
| pH | 5-7.5 |
| Ibintu bifitanye isano | <1.0% |
| Suzuma | 99% |
| Ubushobozi | 1440 - 1680u / mg |
| Kugaragara | Ifu yera hafi yera ifu ya kristaline |
| Igisubizo cyumuti | Ntabwo arenze opalescent kurenza guhagarikwa 1 |
| Kwimura | NLT 90% |
| Butyl acetate | NMT 0,05% |
| Butanol | NMT 0,12% |
e byasobanuwe mbere ko molekile ya autoinducer, yitwa 1,3-diaminopropane (1,3-DAP), isohorwa na Penicillium chrysogenum na Acremonium chrysogenum.Twifashishije imico ya ferment igenzurwa na pH twabonye muri iki gikorwa ko 1,3-DAP na spermidine bitera neza biosynthesis ya benzylpenicillin muri P. chrysogenum, haba mubisobanuro ndetse no mubitangazamakuru bitanga umusaruro wa penisiline.Byombi 1,3-DAP na spermidine, ariko ntabwo ari putrescine (1,4-diaminobutane), bitanga ubwiyongere bukabije bwurwego rwinyandiko-mvugo ya penisiline biosynthetic gen pcbAB, pcbC na penDE.Iyi polyamine ntabwo igira ingaruka kumagambo yisi yose pH-stress igenzura pacC gene, bityo ukuyemo ko ingaruka za 1,3-DAP na spermidine ziterwa no guhindura uburyo bwo kugenzura pH.Kugaragaza ingirabuzima fatizo eshatu za penisiline biosynetike zigabanuka cyane muri laeA-knock-down mutant ya P. chrysogenum, itanga urugero ruke cyane rwa benzylpenicillin.Igishimishije, 1,3-DAP na spermidine ihindura t ingaruka za mutation ya laeA gukubita hasi, igarura rwose urwego rwumusemburo wa penisiline.Byongeye kandi, 1,3-DAP na spermidine byongereye imvugo ya laeA mubibazo byababyeyi kandi bigarura urwego rwinyandiko za laeA muri laeA knock-down mutant.Ufatiye hamwe ibisubizo byerekana ko ingaruka zo gukangura molekules ya inducer 1,3-DAP na spermidine ikoreshwa, byibuze igice, binyuze mukubyutsa imvugo ya laeA, umugenzuzi wisi yose ukora epigenetike mugusobanura genes ya metabolite ya kabiri na heterochromatin kuvugurura.
