N - [(2'-cyano [1,1'biphenyl] -4-yl) methyl] -methyl ester L-valine monohydrochloride CAS: 482577-59-3
Umubare wa Cataloge | XD93425 |
izina RY'IGICURUZWA | N - [(2'-cyano [1,1'biphenyl] -4-yl) methyl] -methyl ester L-valine monohydrochloride |
URUBANZA | 482577-59-3 |
Imiterere ya molekularila | C20H23ClN2O2 |
Uburemere bwa molekile | 358.86 |
Ibisobanuro birambuye | Ibidukikije |
Kugaragaza ibicuruzwa
Kugaragara | Ifu yera |
Assay | 99% min |
N - [((2'-cyanoNi mubyiciro byibiyobyabwenge byitwa angiotensin-ihindura enzyme (ACE) inhibitor.Umuvuduko ukabije wamaraso ni ibintu bisanzwe bishobora kongera ibyago byibibazo byinshi byubuzima, harimo indwara z'umutima, ubwonko, no kwangirika kw'impyiko.Inhibitori ya ACE, nka N - [((2'-cyano imiyoboro y'amaraso. Uburyo bukuru bwibikorwa bya N - [(2'-cyano ).ACE ishinzwe guhindura angiotensin I kuri angiotensin II, vasoconstrictor ikomeye, igabanya imiyoboro y'amaraso kandi ikazamura umuvuduko w'amaraso.Muguhagarika ACE, iyi miti ifasha mukurinda ishingwa rya angiotensin II, biganisha kuri vasodilasiya (kwaguka kwimitsi yamaraso) no kugabanuka kwumuvuduko wamaraso.N - [(2'-cyano [1,1'biphenyl] -4-yl ) methyl] -methyl ester L-valine monohydrochloride isanzwe ifatwa mu kanwa, akenshi nka dosiye rimwe kumunsi.Igipimo cyihariye ninshuro zubuyobozi bizaterwa nibintu bitandukanye, harimo ubukana bwa hypertension hamwe nigisubizo cyumuntu ku kwivuza.Uyu muti urashobora gukoreshwa wenyine cyangwa ufatanije nindi miti igabanya ubukana kugirango ugabanye umuvuduko wamaraso.Ni ngombwa kumenya ko N - [(2'-cyano [1,1'biphenyl] -4-yl) methyl] -methyl ester L-valine monohydrochloride irashobora gutera ingaruka zimwe mubantu bamwe.Ingaruka zisanzwe zirimo kuzunguruka, kubabara umutwe, inkorora yumye, n'umunaniro.Niba izo ngaruka zikomeje cyangwa zikababaza, birasabwa kugisha inama inzobere mubuzima.Mubihe bidasanzwe, ingaruka zikomeye zirashobora kubaho, nka reaction ya allergique, ibibazo byimpyiko, cyangwa angioedema (kubyimba cyane mumaso, iminwa, umuhogo, cyangwa ururimi).Niba hari ingaruka mbi zikomeye zabayeho, hakwiye gushakishwa ubuvuzi bwihuse. Mbere yo gutangira N - [(2'-cyano [1,1'biphenyl] -4-yl) methyl] -methyl ester L-valine monohydrochloride, ni ngombwa kumenyekanisha ubuvuzi buriho cyangwa allergie kwa muganga wanditse.Imiti ntishobora kuba ikwiye kubantu bafite amateka yindwara zimpyiko, indwara zumwijima, cyangwa indwara zumutima, kuko ishobora kuba mbi cyane. Muri make, N - [(2'-cyano [1,1'biphenyl] -4 -yl) methyl] -methyl ester L-valine monohydrochloride ni inhibitor ya ACE ikoreshwa mu kuvura hypertension.Muguhagarika ACE, ifasha kwagura imiyoboro yamaraso no kugabanya umuvuduko wamaraso.Kubahiriza ibipimo byateganijwe, gukurikirana buri gihe ninzobere mu buzima, no gukurikirana ingaruka zishobora guterwa ni ngombwa mu gukoresha neza imiti neza.Ni ngombwa kandi gukomeza ubuzima buzira umuze, harimo imyitozo isanzwe, indyo yuzuye, hamwe no gucunga ibibazo, kugirango turusheho gushyigikira umuvuduko wamaraso.