Metronidazole Cas: 443-48-1
| Umubare wa Cataloge | XD91888 |
| izina RY'IGICURUZWA | Metronidazole |
| URUBANZA | 443-48-1 |
| Imiterere ya molekularila | C6H9N3O3 |
| Uburemere bwa molekile | 171.15 |
| Ibisobanuro birambuye | 2-8 ° C. |
| Amategeko agenga ibiciro | 29332990 |
Kugaragaza ibicuruzwa
| Kugaragara | Ifu ya kirisiti yera |
| Assay | 99% min |
| Ingingo yo gushonga | 159-161 ° C (lit.) |
| Ingingo yo guteka | 301.12 ° C (igereranya) |
| ubucucike | 1.3994 (igereranya) |
| indangagaciro | 1.5800 (igereranya) |
| Fp | 9 ℃ |
| gukemura | acide acike: 0.1 M, isobanutse, umuhondo ucye |
| pka | pKa 2.6 (H2O, t = 25 ± 0.2, Ntasobanuwe) (Ntibizwi) |
| Amazi meza | <0.1 g / 100 mL kuri 20 ºC |
Metronidazole niwo muti wo guhitamo amebiase, trichomonasis yo mu gitsina na trichlomonadic urethritis ku bagabo, lambliose, dysentery ya amebic, n'indwara ya anaerobic iterwa na mikorobe yunvikana ku biyobyabwenge.Synonyme yibi biyobyabwenge ni flagyl, protostat, trichopol, na vagimid.
Metronidazole irahari nkiminwa, intravaginal, topical, hamwe nababyeyi.Yakozwe namasosiyete menshi, ariko iraboneka gusa kubisabwa.Kubangamira ibidukikije utabishaka ntibishoboka, kandi nibibaho, ntibishoboka cyane gutera uburozi.
Ikoreshwa nka antibacterial mukuvura rosacea.Antiprotozoal (trichomonas).Indwara ya kanseri.
Metronidazole, ni antibiyotike na antiprotozoal.Ikoreshwa cyane cyane mu kuvura cyangwa gukumira indwara zandurira muri sisitemu cyangwa zaho ziterwa na bagiteri ya anaerobic, nk'indwara ya bagiteri ya anaerobic yandurira mu cyuho cy'inda, inzira igogora, uburyo bw'imyororokere y'abagore, inzira z'ubuhumekero zo hasi, uruhu n'udutsi tworoshye, amagufwa n'ingingo, n'ibindi. , kwandura meningeal, na colitis iterwa no gukoresha antibiotique nabyo bifite akamaro.Tetanusi ikunze kuvurwa na tetanus antitoxine (TAT).Irashobora kandi gukoreshwa mu kwandura umunwa anaerobic.Ku ya 27 Ukwakira 2017, urutonde rwa kanseri zashyizwe ahagaragara n’ikigo mpuzamahanga cy’umuryango w’abibumbye cyita ku buzima gishinzwe ubushakashatsi kuri kanseri cyatoranijwe mbere kugira ngo gikoreshwe, kandi metronidazole yashyizwe ku rutonde rwa kanseri yo mu cyiciro cya 2B.Muri Mutarama 2020, metronidazole yatoranijwe mu cyiciro cya kabiri cy’urutonde rw’amasoko y’ibihugu bikomatanyije.
Metronidazole nigikorwa cyiza cyane kiboneka mukuvura abantu bafite ubwoko bwose bwa amebiasis, usibye wenda usibye umuntu udafite ibimenyetso ariko akomeza gusohora cysts.Ibyo bintu bisaba amibiside yo mu nda ikora neza, nka diloxanide furoate, sulfate ya paromomycine, cyangwa diiodohydroxyquin.Metronidazole ikora kurwanya amara na sisitemu yo hanze na trophozoite.
Nubwo hydrochloride ya quinacrine yakoreshejwe mu kuvura giardiasis, abaganga benshi bakunda metronidazole.Furazolidone nubundi buryo bwo guhitamo.
Metronidazole niwo muti uhitamo i Burayi kwandura bagiteri ya anaerobic;impungenge zatewe na kanseri ishobora gutera abantu kwitonda mugukoresha muri Amerika. Vuba aha byagaragaye ko ari ingirakamaro mu kuvura indwara zanduye D. medinensis (Gineya) na Helicobacter pylori.
Ikoreshwa kandi muri acne rosacea, balantidiasis na Gineya yanduye.Indwara ya T. vaginalis irwanya dosiye isanzwe isaba ubuvuzi bwihariye.
