CAS ya Losartan: 114798-26-4
Umubare wa Cataloge | XD93387 |
izina RY'IGICURUZWA | Losartan |
URUBANZA | 114798-26-4 |
Imiterere ya molekularila | C22H23ClN6O |
Uburemere bwa molekile | 422.91 |
Ibisobanuro birambuye | Ibidukikije |
Kugaragaza ibicuruzwa
Kugaragara | Ifu yera |
Assay | 99% min |
Losartan ni imiti iri mubyiciro byibiyobyabwenge bizwi nka angiotensin II reseptor blokers (ARBs).Ikoreshwa cyane cyane mukuvura umuvuduko ukabije wamaraso (hypertension) nubwoko bumwe na bumwe bwimiterere yumutima.Umuvuduko ukabije wamaraso ni indwara isanzwe irangwa no kuzamuka kwumuvuduko wamaraso.Iyo itavuwe, irashobora gukurura ingorane zikomeye zubuzima nkindwara z'umutima, ubwonko, nibibazo byimpyiko.Losartan ikora ihagarika imikorere ya hormone yitwa angiotensin II, igabanya imiyoboro y'amaraso kandi igatera umuvuduko w'amaraso kwiyongera.Muguhagarika iyi misemburo, losartan ifasha kuruhuka no kwagura imiyoboro yamaraso, bityo bikagabanya umuvuduko wamaraso. Usibye kuvura hypertension, losartan nayo igirira akamaro indwara zimwe na zimwe z'umutima, nko kunanirwa k'umutima hamwe na hypertrophy ibumoso.Irashobora gufasha kunonosora ibimenyetso, kongera imikorere yumutima, no kugabanya ibyago byindwara zifata umutima nimiyoboro yabarwayi bafite ibi bibazo.Ikindi kandi, losartan yasanze ifite ingaruka zo kurinda impyiko kubantu barwaye diyabete yo mu bwoko bwa 2 na diabete ya diabete (indwara yimpyiko).Irashobora kudindiza iterambere ryangirika ryimpyiko, kugabanya proteinuria (proteine zirenze inkari), kandi bigafasha kubungabunga imikorere yimpyiko muri aba bantu. Gukoresha no gukoresha losartan birashobora gutandukana bitewe nubuzima bwumuntu, imyaka, nibindi bintu.Ubusanzwe ifatwa mu kanwa rimwe kumunsi, hamwe cyangwa ibiryo.Ni ngombwa gukurikiza ibipimo byateganijwe n'amabwiriza yatanzwe ninzobere mu by'ubuzima.Nk'imiti iyo ari yo yose, losartan irashobora kugira ingaruka mbi.Ingaruka zisanzwe zishobora kubamo umutwe, umunaniro, kubabara umutwe, no kuribwa mu gifu.Birasabwa kumenyesha ingaruka zose zikomeye cyangwa zihoraho kubashinzwe ubuzima.Mu ncamake, losartan ni angiotensin II ikumira reseptor ikunze gukoreshwa mu kuvura hypertension, indwara z'umutima nko kunanirwa k'umutima, na nepropatique diabete.Muguhagarika ibikorwa bya angiotensin II, losartan ifasha kuruhuka no kwagura imiyoboro yamaraso, bityo bikagabanya umuvuduko wamaraso no kunoza imikorere yumutima.Numuti wingenzi mugucunga ibi bihe kandi ugomba gufatwa nkuko byerekanwa ninzobere mubuzima.