Lipase iva pancreas pancreas CAS: 9001-62-1 Umuhondo kugeza ifu ya beige
| Umubare wa Cataloge | XD90387 |
| izina RY'IGICURUZWA | Lipase iva pancreas |
| URUBANZA | 9001-62-1 |
| Inzira ya molekulari | N / A. |
| Uburemere bwa molekile | N / A. |
| Ibisobanuro birambuye | 2 kugeza 8 ° C. |
| Amategeko agenga ibiciro | 35079090 |
Kugaragaza ibicuruzwa
| Ivu | <12% |
| AS | <2mg / kg |
| Pb | <2mg / kg |
| Ibirimo Amazi | <8% |
| Suzuma | 99% |
| Igikorwa cya Enzyme | > 30000u / g |
| Kugaragara | Ifu yijimye |
| Itsinda rya Coliform | <30MPH / 100g |
| Kubushakashatsi ukoreshe gusa, ntabwo ari ugukoresha abantu | gukoresha ubushakashatsi gusa, ntabwo ari ugukoresha abantu |
Guhindura metabolism ya triglyceride (TG) mungirangingo yimitsi itwara imitsi (SMC) birashoboka ko bifitanye isano na fenotipike imwe n'imwe, nubwo ibi bitigeze bisobanurwa.Adipose triglyceride lipase (ATGL) ikora ibikorwa byingenzi bya catalitiki ya TG muri selile adipotic na adipotic selile.Muri ubu bushakashatsi, twatandukanije SMC n'imbeba zabuze ATGL (ATGL (- / -) mSMC).ATGL (- / -) mSMC yerekanye kwirundanya kwa TG bidatinze hamwe na mitogenic yo hasi hamwe n'imikorere ya imitsi ya actin (SMA) ugereranije na ATGL (+ / +) mSMC.Ijanisha rya senescence ifitanye isano _-galactosidase selile nziza nayo yariyongereye muri ATGL (- / -) mSMC.Igihe nyacyo PCR ikurikirwa no gusuzuma hamwe nisesengura ryibanze rya ADN ryagaragaje imvugo igenga glucokinase (inshuro 1.7), lipase ya lipoprotein (inshuro 3.8) na interleukin-6 (inshuro 3.7) hamwe no kugabanuka kumagambo yo gukura kw'imitsi iva mu mitsi. ikintu-A (0.2-inshuro), andika I kolagen (inshuro 0,5), no guhindura ibintu bikura-_ (0.4-inshuro) muri ATGL (- / -) mSMC ugereranije na ATGL (+ / +) mSMC.Ibikurikira, ihererekanyabubasha rya gene ya ectopique ya ATGL yagerageje gukoresha doxycycline (Dox) -igenzurwa na myc-DDK-yashizweho na adenovirus vector (AdvATGL).Indwara ya AdvATGL yatumye igabanuka rya TG hamwe nigisubizo cya mitogenic hamwe nigisubizo cya SMA, kandi kigabanuka mumibare yimikorere ya senescent muri ATGL (- / -) mSMC.Byongeye kandi, uburyo bwo kwerekana imiterere ya gene muri ATGL (- / -) mSMC byashobokaga gukosorwa.Amakuru yacu yerekana ko ATGL (- / -) mSMC ifite fenotipike itandukanye ishobora kuba ifitanye isano na virusi itera indwara.Plastike ya SMC phenotypes ifitanye isano na lipide metabolism ishobora kuba intego yo kuvura.
