L-Tryptophan Cas: 73-22-3 99% Ifu yera
| Umubare wa Cataloge | XD90295 |
| izina RY'IGICURUZWA | L-Kugerageza |
| URUBANZA | 73-22-3 |
| Inzira ya molekulari | C11H12N2O2 |
| Uburemere bwa molekile | 204.22518 |
| Ibisobanuro birambuye | Ibidukikije |
| Amategeko agenga ibiciro | 29339980 |
Kugaragaza ibicuruzwa
| Suzuma | 99% min |
| Kugaragara | Ifu yera |
| Icyiciro | USP32 |
| Kuzenguruka byihariye | -29.4 kugeza -32.8 |
| pH | 5.5 kugeza 7.0 |
| Fe | <0.003% |
| Pb | <0.0015% |
| Gutakaza Kuma | <0.3% |
| Ibisigisigi kuri Ignition | 0.1% max |
| Cl | 0,05% |
Indoleamine 2,3-dioxygenase (IDO1) na tryptophan 2,3-dioxygenase (TDO) ni imisemburo ibiri itandukanye mu buryo butandukanye ikwirakwiza ingirabuzimafatizo zitandukanye hamwe ninshingano za physiologique, ariko byombi bitera ihinduka rya tripitofani na N-formylkynurenine (NFK).IDO1 yemejwe mu buvuzi nk'intego ntoya ya molekile yibasira kanseri, mu gihe ubushakashatsi bwibanze bwerekana ko TDO ishobora kuba intego yo gukingira kanseri n'indwara zifata ubwonko.Twateje imbere ubushakashatsi bwimbitse kuri IDO1 na TDO dushingiye ku bushakashatsi bushya bw’imiti, NFK Green, bwitwara neza hamwe na NFK gukora molekile yicyatsi kibisi ifite uburebure bwa 400 nm hamwe nuburebure bwa 510 nm.Turatanga igereranya ryambere kuruhande rwibintu byinshi byashyizwe ahagaragara byerekana inhibitori ya IDO1 na TDO kandi tugaragaza ko indangamuntu ya IDO1 inhibitor Compound 5l yerekana uburyo bukomeye bwo guhuza ibikorwa na TDO, mugihe byemejwe ko guhitamo kwizindi nzitizi zashyizwe ahagaragara byemejwe.Ikariso ya itabil yo kwisuzumisha hejuru yerekana ubushakashatsi yerekanwe no kwerekana isomero ryibintu 87.000 byimiti muburyo bwa 384- cyangwa 1536-neza.Hanyuma, twerekana ko isuzuma rishobora no gukoreshwa mugupima ubushobozi bwingirabuzimafatizo zo guhinduranya tryptophan no gupima imbaraga za selile ya IDO1 na TDO inhibitor.
