Ibicuruzwa

Imiterere yumubiri na chimique ya threonine

Kugaragara: ifu yera

Incamake

L.Bikunze kongerwa mubiryo byingurube ningurube, kandi nubwa kabiri bigabanya aside amine mu biryo byingurube naho icya gatatu kigabanya aside amine mu biryo by’inkoko.Ongeramo L-threonine mu biryo bivanze bifite ibintu bikurikira: can Irashobora guhindura aside irike ya aminide yibiryo kandi igatera imbere gukura kwamatungo;Can Irashobora kuzamura ubwiza bwinyama;Can Irashobora kuzamura agaciro k'imirire y'ibiryo hamwe na acide ya amino acide;Can Irashobora kugabanya ikiguzi cyibikoresho byibanze;kubwibyo, yakoreshejwe cyane mu nganda zigaburira mu bihugu by’Uburayi (cyane cyane Ubudage, Ububiligi, Danemarke, n’ibindi) no mu bihugu by’Amerika.

Menya

Yatandukanijwe kandi yamenyekanye muri fibrin hydrolyzate na WCRose1935.Mu 1936, Meger yize imiterere yacyo kandi ayita threonine kubera imiterere isa na threose.Hariho isomeri enye za threonine, na L-threonine nimwe ibaho bisanzwe kandi igira ingaruka kumubiri.

inzira ya metabolike

Inzira ya metabolike ya threonine mumubiri itandukanye nizindi aside amine.Niyo yonyine idakorerwa dehydrogenase no kwanduzwa, ahubwo ikoresheje dehydratase ya threonine (TDH) hamwe na dehidrasi ya threonine (TDG) hamwe na aldehyde.Amino acide ihindurwa mubindi bintu itangizwa na enzymes.Hariho inzira eshatu zingenzi: metabolised to glycine na acetaldehyde na aldolase;metabolised to acide aminopropionic, glycine, na acetyl COA na TDG;metabolised to aside protionic na α-aminobutyric aside na TDH

Gukoresha ibicuruzwa bya Threonine

Intego nyamukuru

Threonine ningirakamaro zintungamubiri, zishobora gushimangira ibinyampeke, imigati, nibikomoka ku mata.Kimwe na tripitofani, irashobora kugabanya umunaniro wabantu no guteza imbere gukura niterambere.Mu buvuzi, kubera ko imiterere ya threonine irimo amatsinda ya hydroxyl, igira ingaruka zifata amazi ku ruhu rwabantu, zifatanije n’iminyururu ya oligosaccharide, igira uruhare runini mu kurinda uturemangingo, kandi irashobora guteza imbere synthesis ya fosifolipide na okiside ya aside irike mu mubiri.Imyiteguro igira ingaruka zubuvuzi zo guteza imbere iterambere ryabantu no kurwanya umwijima wamavuta, kandi nikintu kigizwe na aside amine acide.Muri icyo gihe, threonine nayo ni ibikoresho fatizo byo gukora icyiciro cya antibiyotike nziza cyane na hypoallergenic, monoamidocine.

Inkomoko yibiryo byingenzi: ibiryo byasembuwe (ibicuruzwa byimbuto), amagi, chrysanthem, amata, ibishyimbo, umuceri, karoti, imboga zibabi, papayi, alfalfa, nibindi.

Threonine ikoreshwa mubuvuzi, imiti igabanya ubukana, ibyokurya byongera ibiryo, inyongeramusaruro, nibindi. Byumwihariko, ingano yinyongera yibiryo yiyongereye vuba.Bikunze kongerwa mubiryo byingurube ningurube, kandi nubwa kabiri bigabanya aside amine mu biryo byingurube naho icya gatatu kigabanya aside amine mu biryo by’inkoko.[4]

Hamwe no kuzamura imibereho yabantu no guteza imbere ubuhinzi bw’amafi, threonine, nka aside amine yo kugaburira, ikoreshwa cyane mu kongeramo ibiryo by’ingurube, korora ibiryo by’ingurube, ibiryo bya broiler, ibiryo bya shrimp hamwe n’ibiryo bya eel.Ifite ibi bikurikira:

——Guhindura ingano ya aside amine mu biryo kugirango uteze imbere;

- irashobora kuzamura ubwiza bwinyama;

- irashobora kuzamura intungamubiri yibiribwa hamwe na acide ya amino acide;

——Bishobora gutanga ibiryo bike bya poroteyine, bifasha kubika umutungo wa poroteyine;

——Bishobora kugabanya ikiguzi cyibikoresho fatizo;

——Bishobora kugabanya azote iri mu bworozi n’ifumbire y’inkoko n’inkari, hamwe n’igipimo cya amoniya hamwe n’irekurwa mu matungo n’inkoko.

Kugeza ubu, abahanga mu bya siyansi b'Abadage bavumbuye threonine mu maraso y’abantu, kandi ubushakashatsi bwerekanye ko bushobora kubuza virusi itera SIDA kwanduza no gutera selile zimwe na zimwe, mu kwivanga kuri poroteyine yo hejuru ya virusi itera sida, bigatuma idashobora gukora.Ivumburwa rya aside amine itanga inzira yo guteza imbere imiti irwanya SIDA.

Gukenera gusaba kugaburira

Kugeza ubu, ugereranije no kubura amikoro, cyane cyane kubura ibiryo bya poroteyine nk'ifunguro rya soya n'ifunguro ry'amafi, bibuza cyane iterambere ry'ubworozi.Ubusanzwe Threonine ni iya kabiri cyangwa iya gatatu igabanya aside amine mu biryo by'ingurube, naho iya gatatu cyangwa iya kane igabanya aside amine mu biryo by'inkoko.Hamwe nogukoresha kwinshi kwa lysine na methionine yubukorikori bwibiryo byimbuto, bigenda buhoro buhoro Byahindutse ibintu nyamukuru bigabanya ingaruka zimikorere y’amatungo n’inkoko, cyane cyane nyuma yo kongeramo lysine mu mafunguro ya poroteyine nkeya, threonine ibaye aside ya mbere igabanya aside amine gukura ingurube.

Niba threonine idakoreshwa mu biryo, amabwiriza ya threonine mu biryo ashobora gusa gushingira ku bikoresho fatizo bya poroteyine, kandi ibikoresho fatizo bya poroteyine ntibirimo threonine gusa, ahubwo binafite andi acide ya amine acide kandi atari ngombwa.Igisubizo cyo gukoresha threonine kugirango uhindure ingano ya aside amine ni uko ingano ya aside amine yibiryo idashobora kunozwa uko bishoboka kwose, imyanda ya acide aminide yingirakamaro ntishobora kugabanuka, hamwe nigiciro cyibiryo byibiryo ntishobora kugabanuka.Imipaka igomba kurenga kugirango irusheho kuringaniza aside amine nikibazo cyikibazo abayikora bose badashobora kwirinda.

Gukoresha threonine birashobora kugabanya imyanda ya acide yingenzi kandi idakenewe, cyangwa kugabanya urwego rwa poroteyine rwibiryo rwibiryo.Impamvu ni kimwe no gukoresha lysine hydrochloride.Urwego rwa poroteyine rwibanze rwibiryo rushobora kuboneka ukoresheje acide kristaline.Kugabanuka ku buryo bushyize mu gaciro, imikorere y’inyamaswa ntizangirika, ariko irashobora kunozwa.