Ibicuruzwa

7-Hydroxygranisetron nuruvange rukora nk'imiti mubijyanye n'ubuvuzi.Ni mubyiciro byibiyobyabwenge bizwi nka selotonine yatoranijwe 5-HT3 reseptor antagonist.Uru ruganda ni metabolite ya granisetron, imiti ikoreshwa cyane.Intego nyamukuru ya 7-Hydroxygranisetron ni ukurinda no kuvura isesemi no kuruka, cyane cyane ibijyanye na chimiotherapie cyangwa uburyo bwo kubaga. Chimoterapi iterwa no kugira isesemi no kuruka (CINV) ni impungenge zikomeye ku barwayi ba kanseri bavurwa.Izi ngaruka mbi zirashobora kugira ingaruka mbi kumibereho yumurwayi kandi bishobora kuviramo guhungabana.7-Hydroxygranisetron ikora ihagarika reseptor ya serotonine yihariye muri sisitemu yo hagati yo hagati, cyane cyane iyo muri chemoreceptor trigger zone hamwe no kuruka.Mugukora utyo, bifasha kugabanya ibimenyetso bitera isesemi no kuruka, bitanga ubutabazi kubarwayi. Usibye kuba yarakoresheje CINV, 7-Hydroxygranisetron yanagaragaje amasezerano mugucunga isesemi na kuruka nyuma yibikorwa (PONV).Nyuma yuburyo bwo kubaga, abarwayi bakunze kwibasirwa no kugira isesemi no kuruka bitewe ningaruka za anesteya nibindi bintu.7-Hydroxygranisetron ifasha mukurinda no kugenzura ibyo bimenyetso, bigatuma abarwayi bakira neza.Iyo itanzwe, 7-Hydroxygranisetron isanzwe itangwa mumitsi cyangwa mumanwa, bitewe nuburwayi bwumurwayi nibisabwa mubuvuzi.Igipimo gishobora gutandukana ukurikije ibintu nkuburemere bwumuntu, uburyo bwihariye cyangwa ubuvuzi, hamwe nuburemere bwibimenyetso.Ni ngombwa gukurikiza urugero rwateganijwe n'amabwiriza yatanzwe ninzobere mu buvuzi kugira ngo habeho gukora neza no kwirinda ingaruka zose zishobora kubaho.Nk'imiti myinshi, 7-Hydroxygranisetron irashobora kugira ingaruka mbi.Ibi bishobora kubamo umutwe, kuribwa mu nda, impiswi, umutwe, n'umunaniro.Mubihe bidasanzwe, abantu barashobora guhura na allergique cyangwa ingaruka mbi zikomeye.Ni ngombwa kumenyesha ibimenyetso byose bijyanye nibimenyetso cyangwa ibisubizo kubashinzwe ubuzima kugirango basuzume kandi babicunge neza. Mu gusoza, 7-Hydroxygranisetron ni imiti ikoreshwa cyane cyane mu gukumira no kuvura isesemi no kuruka bijyana na chimiotherapie hamwe n’uburyo bwo kubaga.Muguhagarika bimwe mu byakira serotonine muri sisitemu yo hagati, bifasha kugabanya ibi bimenyetso bibabaza abarwayi ba kanseri nabantu bakira kubagwa.Ariko, kimwe n'imiti iyo ari yo yose, ni