Ibicuruzwa

Imikoranire hagati yimiti igabanya ubukana, Metformin na inyana ya thymus ADN (CT-ADN) muri (50mM Tris-HCl) buffer yakozwe na UV-Visible absorption, fluorescence, CD spectroscopy hamwe no gupima viscosity.Mu bushakashatsi bwa fluorimetric, ishyaka na entropy byimyitwarire hagati yibiyobyabwenge na CT-ADN byagaragaje ko reaction ari exothermic (ΔH = -35.4522 kJ mol (-1); ΔS = -49.9523 J mol (-1) K (-1) )).Ubushakashatsi buhuza amarushanwa bwerekanye ko ibiyobyabwenge bishobora kurekura Hoechst 33258 burundu.Urusobekerane rwerekanaga hyperchromism yo kwinjiza muri UV-Vis ya ecran hamwe na ADN.Ibiharuro bibarwa bihoraho, K (b), byakuwe mubushakashatsi bwakorewe UV-Vis byari 8.3 × 10 (4) M (-1).Byongeye kandi, impinduka muri CD yerekanwe imbere yibiyobyabwenge byerekana ko ihagaze ryuburyo B bwiburyo bwa CT-ADN.Hanyuma, ibipimo byijimye byerekanaga ko guhuza uruganda na CT-ADN bishobora guhuza ubuso, ahanini biterwa no guhuza ibiti. Copyright © 2012 Elsevier BV Uburenganzira bwose burasubitswe.