Ibicuruzwa

Indwara ya Ischemic yerekanwe ko itera hypermetabolism ya glucose muri ischemic penumbra.Ubushakashatsi hamwe nubuvuzi bwerekana ko hyperglycemia ifitanye isano na infarct ari intego yo kuvura indwara yubwonko bukabije.Nyamara, ubushakashatsi bw’amavuriro bugamije kurwanya glucose mu bwonko bukabije ntabwo bwateje imbere imikorere cyangwa ngo bugabanye impfu.Rero, ubushakashatsi bwimbitse kuri glucose metabolism mubwonko bwa ischemic buremewe.Twakoresheje urugero rwimbeba yimitsi irinda ingwate.Inyamaswa zasesenguwe na [2- (18) F] -2-fluoro-2-deoxy-d-glucose positron yoherejwe na tomografiya cyangwa magnetiki resonance yerekana amashusho mugihe cyiminota 90 ifata imiyoboro yubwonko bwo hagati no muminota 60 nyuma yo kwisubiraho.Ibisubizo byari bifitanye isano na magnetiki resonance yerekana amashusho yubwonko bwubwonko, ikwirakwizwa ryamazi, imiterere ya lakate, hamwe namakuru yamateka yerekeye urupfu rw'uturemangingo no kumeneka kw'ubwonko bwamaraso. Twabonye ko kwiyongera [2- (18) F] -2-fluoro-2 -deoxy-d-glucose gufata muri ischemic re gions yatewe na infarction no mukarere ka peri-infarct.Amashusho ya Magnetic resonance yerekana ko umuvuduko wamaraso ugabanuka kurwego rwa ischemic muri infarct no kugabanuka kwamaraso yubwonko mu karere ka peri-infarct.Magnetic resonance spectroscopy yerekanye lactate mukarere ka ischemic no kutagira lakate mukarere ka peri-infarct.Isesengura rya Immunohistochemical ryerekanye ko apoptose hamwe nubwonko bwamaraso bwangirika muri infarct. Kwiyongera kwa [2- (18) F] -2-fluoro-2-deoxy-d-glucose muri ischemia cerebral birashoboka cyane ko byerekana hypermetabolisme yinama ya glucose yongerewe ingufu ibikenerwa byubwonko bwa ischemic na hypoperfused ubwonko, kandi bibaho mubihe byombi bya anaerobic na aerobic byapimwe numusemburo waho.Infarct ifitanye isano na hyperglycemia sisitemu ishobora gufasha koroshya glucose ubwonko bwa ischemic.Igenzura rya glycemic ukoresheje insuline rishobora kugira ingaruka mbi kuri ubu buryo.