Cyclosporin A CAS: 59865-13-3 Ifu ya kirisiti yera 99%
Umubare wa Cataloge | XD90346 |
izina RY'IGICURUZWA | Cyclosporin A. |
URUBANZA | 59865-13-3 |
Inzira ya molekulari | C62H111N11O12 |
Uburemere bwa molekile | 1202.61 |
Ibisobanuro birambuye | 2 kugeza 8 ° C. |
Amategeko agenga ibiciro | 29419000 |
Kugaragaza ibicuruzwa
Suzuma | 99% |
Kugaragara | Ifu ya kirisiti yera |
Icyiciro | USP 35 |
Umwanda | Umwanda wose: 0,6% max, Impinduka imwe imwe: 0.2% |
Ibyuma biremereye | 20ppm max |
Acetone | 10ppm |
Gutakaza Kuma | 2.0% max |
Ubushyuhe Ububiko | + 4% |
Kugaragara k'umuti | Igisubizo nkuko bisobanurwa muri EPIV |
Ibikomoka kuri peteroli | 31ppm |
Ibyiza: Ifu yera cyangwa itari yera, impumuro nziza kandi itaryoshye.Irashobora gushonga byoroshye muri methanol, Ethanol cyangwa acetonitrile, gushonga byoroshye muri Ethyl acetate, gushonga muri acetone cyangwa ether, kandi hafi yo kudashonga mumazi.Ihinduranya ryihariye ryibicuruzwa bigenwa nigitabo cyimiti, hanyuma kigashonga muri methanol kugirango kibe igisubizo kirimo mg 10 kuri ml 1.Kuzenguruka byihariye ni -182 ° kugeza kuri -192 °.Gukoresha: ubushakashatsi bwibinyabuzima.Kubuza T selile reseptor yerekana inzira
Iki gicuruzwa nubwoko bushya bwa immunosuppressant.Nibintu bya cyclic polypeptide bigizwe na acide cumi nimwe ya amino.Irwanya imikorere yumubiri itwenza kandi itangwa na selile idakumira igufwa ryamagufwa kandi igabanya umubare wamaraso yera.Irashobora gukumira kwangwa ingirangingo cyangwa urugingo rwimiti.Ikoreshwa mubuvuzi muguhindura impyiko, umwijima, ibihaha no guhinduranya umutima.Byongeye kandi, igira ingaruka zimwe na zimwe zo gukiza indwara ziterwa na autoimmune, ndetse na schistosomiasis, malariya, diyabete, sida, nibindi, ndetse nuburyo bwo kurwanya inflammatory.
Kuvura leukemia, kanseri, guhinduranya impyiko, igituntu, nibindi