Ibicuruzwa

Clopidogrel camphorsulfonate nuruvange rwa farumasi hamwe na formula ya chimique C16H16ClNO2S · C10H16O4S.Bizwi cyane nka Clopidogrel S-oxide camphorsulfonate cyangwa Clopidogrel CAMS.Uru ruganda ni chiral ikomoka kuri clopidogrel, niwo muti ukoreshwa cyane na antiplatelet.Ikoreshwa ryambere rya Clopidogrel camphorsulfonate ni kimwe mu bintu bigira uruhare runini mu gutegura imiti igabanya ubukana.Ikora mukubuza gukusanya platine, kurinda amaraso gutembera, no kugabanya ibyago byo kurwara umutima.Uru ruganda rwibanda cyane cyane kuri reseptor ya P2Y12 kuri platine, bityo bikabuza inzira yo gukora kandi bikabuza gukusanya platine.Ubu buryo bwibikorwa butuma Clopidogrel camphorsulfonate igira akamaro mukurinda trombose ya arterial no kugabanya indwara ziterwa nindwara zifata umutima, harimo n'indwara z'umutima ndetse na stroke.Clopidogrel camphorsulfonate ikorwa mumanwa muburyo bwa tableti cyangwa capsules.Iyo imaze kwinjizwa, ihinduka metabolike mu mwijima, bigatuma habaho metabolite ikora.Iyi metabolite ikora noneho ihuza bidasubirwaho na reseptor ya P2Y12, ikoresha ingaruka zayo za antiplatelet mugihe kinini.Uru ruganda rufite igihe kirekire cyo gukora, rusaba kunywa inshuro imwe kumunsi mubihe byinshi.Mu mavuriro, Clopidogrel camphorsulfonate isanzwe yandikiwe abarwayi bafite syndromes ikaze ya coronary, nka angina idahindagurika hamwe na infocarite myocardial, cyangwa ababa barwaye coronary percutaneous. intervention (PCI) hamwe no gushyira stent.Irakoreshwa kandi cyane mukurinda ko habaho ibintu bya trombotique kubarwayi bafite amateka yubwonko cyangwa indwara ya arteriire.Imikoreshereze ya Clopidogrel camphorsulfonate ikunze guhuzwa na aspirine nkeya kugirango igabanye imiti igabanya ubukana.Ni ngombwa kumenya ko Clopidogrel camphorsulfonate igomba gukoreshwa gusa iyobowe ninzobere mubuzima, kuko ishobora gukorana nindi miti cyangwa ikagira imiti igabanya ubukana muri bimwe. abaturage barwayi.Ingano nigihe cyo kwivuza birashobora gutandukana bitewe nubuzima bwumuntu ku giti cye, kandi gukurikirana buri gihe imikorere ya platine no gupima amaraso birashobora gukenerwa kugirango habeho uburyo bwiza bwo kuvura.Mu ncamake, Clopidogrel camphorsulfonate nikintu cyingenzi mugucunga indwara zifata umutima, cyane cyane ibijyanye na arterial trombose.Imiterere ya antiplatelet hamwe no guhitamo guhitamo reseptor ya P2Y12 bituma iba imiti ifatika yo kugabanya ibyago byindwara zifata umutima.Icyakora, kimwe n’ibindi bikoresho bivura imiti, hagomba kwitonderwa mu mikoreshereze yabyo, kandi abarwayi bagomba kubahiriza ibyifuzo by’ubuvuzi ndetse n’ubuyobozi.